Germ-line and somatic mutations of the hSNF5/INI1 gene have been reported in atypical teratoid/rhabdoid tumors (AT/RTs) of the brain, consistent with its role as a tumor suppressor gene. In the present study, we determined the frequency of deletions and mutations of INI1 in 52 children whose original diagnosis was medulloblastoma (MB) or primitive neuroectodermal tumor (PNET) of the central ner...

Pr imary intraspinal pr imit ive neuroecto dermal tumors (PNETs) are rare. We report a case of sacral PNET with review the literature. A 15 -yearold boy presented w ith progres sive lumbar area pain, lower leg numbness and neurogenic bladder. Preoperat ive magnet ic resonance imag ing revealed a sacral tumor with epidural, presacral, and sacral bone extensions. An urgent operation was performed...

Solid pseudopapillary tumor of the pancreas (SPTP) is a class of low-grade malignant tumors that carry a favorable prognosis after surgery. Our group has reported that dysfunctions in the endoplasmic reticulum (ER) protein processing pathway may play a role in tumor development. However, alterations of this pathway in other pancreatic tumors had not been well investigated. In this study, we col...

Primitive neuroectodermal tumor (PNET) and Ewing’s sarcoma (EWS) are small round cell tumors occurring mainly in children and adolescents, rarely in adults. It can occur in multiple tissues and organs including kidney, adrenal, bladder, liver, small intestine, colon and rectum, with a preferred location within the chest area, in the limbs and around the spine, but with rare cases of abdominal, ...

Renal primitive neuroectodermal tumor (renal PNET) or renal Ewing sarcoma ES) is a rare, rapidly growing malignant small round cell with poor prognosis. A 32-years-old Bangladeshi male patient presented right loin pain, fever and anemia. On CT imaging large (18x10.5x10.0 cm) mass was discovered. suspicion of malignancy, biopsy taken from the mass. Microscopic evaluation showed features consiste...

background pancreatic neuroendocrine tumors (pnets) are rare tumors with variable malignant potential, prognosis, and survival. we aimed to assess the characteristics of patients with non- functional pnet  in our hospital . methods from nov 2010 to nov 2013 , all patients who came to endosonography unit of shariati  hospital , tehran , iran , and   had pancreatic lesions were assessed . tumor s...

Solid pseudopapillary tumors (SPT) are rare, unique pancreatic tumors with benign entity and low malignant potential. Limited information is available in the literature reporting their accumulation of fluorine-18 fluoro deoxyglucose ((18)F-FDG) using positron emission tomography/computed tomography (PET/CT). The aim of this retrospective study was to define t he uptake-accumulation of (18)F-FDG...