Background and aims Peroral endoscopic myotomy (POEM) is now an established treatment for esophageal achalasia. The standard protocol ensures a smooth operation in most patients, but technical challenges and failures exist and little is known about the incidence, causes, and impact of aborted procedures. Here, using a large patient cohort, we attempted to answer these questions. Methods All pat...

BACKGROUND Based on Chicago Classification version 3.0, the disorders of esophagogastric junction outflow obstruction (EGJOO) include achalasia (types I, II and III) and EGJOO. Although no curative treatments are currently available for the treatment of the disorders of EGJOO, medical treatments, endoscopic pneumatic dilation (PD), laparoscopic Heller myotomy (LHM), and per-oral endoscopic myot...

esophageal spasm Diffuse esophageal spasm (DES) is a rare esophageal dysmotility condition characterized by simultaneous contractions of the distal esophagus and manifested by dysphagia and chest pain. Pharmacological therapy, endoscopic interventions, and surgical myotomy have been linked to various outcomes [1,2]. Recently, peroral endoscopic myotomy (POEM) has been introduced as an effective...

BACKGROUND Despite over a decade of research and technological advances, sublingual microcirculatory monitoring has not yet reached clinical utility. Offline analysis is time consuming and occurs away from the patient. A system to assess the microcirculation at the point of care is desirable. We present a novel 5-point grading system (the point of care microcirculation (POEM) scoring system) th...

abdol sabur the poet of this age is one of the best poets of egyptafter ahmad shoghi that go to north and he has different experiences in several genere such as drama and poem. he used from survivor of thought of god in his poem. that is most important characterist of his poem, and he tried to approach this - characteristic to the poem. one of the most important topics that poem of this age wit...

"A Valediction: Forbidding Mourning" shows many features associated with seventeenth-century metaphysical poetry in general, and with Donne's work in particular. Donne's contemporary, the English writer Izaak Walton, tells us the poem dates from 1611, when Donne, about to travel to France and Germany, wrote for his wife this valediction, or farewell speech. Like most poetry of Donne's time, it ...

Whereas building and enriching ontologies are complex and tedious tasks, only few tools propose a complete solution to assist users. This paper presents POEM (Platform for Ontology crEation and Management) which provides a complete environment for ontology building, merge and evolution. POEM’s algorithms are based on existence constraints and Boolean equations that allow to capture the semantic...