BACKGROUND Dermatomyositis (DM) is an autoimmune disease characterized by cutaneous Gottron papules, heliotrope rash, and proximal myopathy. It may also present as a paraneoplastic syndrome that can complicate a variety of different cancers, such as lung, cervical, and breast cancer. However, the association with hepatocellular carcinoma (HCC) is extremely rare. Moreover, to our knowledge, ther...

Ravindran R. BMJ Case Rep 2017. doi:10.1136/bcr-2014-203856 Description Prolonged abdominal heat application in an individual with diabetes and gastroparesis leads to the development of erythema ab igne. Practitioners should be aware of the various ways that erythema ab igne can present. Erythema ab igne is due to prolonged heat exposure (43–47°C) which causes damage to superficial vascular ple...

Xeroderma pigmentosum (XP) is a rare autosomal recessive genetic disorder characterized by defective DNA repair leading to clinical and cellular hypersensitivity to ultraviolet (UV) radiation and carcinogenic agents. Important clinical features are: Intense cutaneous photosensitivity, xerosis, poikiloderma, actinic keratosis, acute burning under minimal sun exposure, erythemas, hyperpigmented l...

Cutaneous involvement is a prominent feature in connective tissue disease and the skin lesions are extremely important in diagnosing and subclassifying patients with these conditions. Fifty cases of connective tissue diseases of skin were studied over a period of two years to analyze overlapping of histopathological features, possible transformation of one disease to the other and co-existing c...

INTRODUCTION Nonmelanoma skin cancer is the most common malignancy in white individuals. The risk factors for squamous cell carcinoma, which belongs to the family of nonmelanoma skin cancers, have not been studied in Colombia. OBJECTIVE To determine the risk factors for squamous cell carcinoma in patients at a national referral center for skin diseases in Colombia. MATERIAL AND METHODS We c...

Kindler syndrome is a rare autosomal-recessive genodermatosis characterized by bullous poikiloderma with photosensitivity. We report the localization to chromosome 20p12.3 by homozygosity mapping and the identification of a new gene, which we propose to name kindlerin. We found four different homozygous mutations in four consanguineous families from North Africa and Senegal; three are expected ...

BACKGROUND AND OBJECTIVES Intense pulsed light (IPL) systems are high-intensity light sources, which emit polychromatic light. Unlike laser systems, these flashlamps work with noncoherent light in a broad wavelength spectrum of 515-1,200 nm. These properties allow for great variability in selecting individual treatment parameters and adapting to different types of skin types and indications. Th...

Mycosis fungoides (MF) is one of the most common primary cutaneous T-cell lymphoma, whose early stages, especially patch stage poses a diagnostic challenge, as it presents quite similarly to other inflammatory skin diseases and chronic dermatoses. We present a case of a 31-year-old young male presented to us with complaints of generalized hyperpigmentation associated with mild itching since 4 y...