Biomass, a renewable carbon source which can be processed using biorefinery system as an alternative of the conventional petroleum-based refineries. Aromatic precursor molecule synthesis involves chemical fossil-fuel-based starting materials, such benzene and xylene. These energy-intensive processes are usually producing many byproducts along with desired molecule. If aromatic molecules extract...

Meta-aminobenzoic acid, an important model system in the study of polymorphism and crystallization of active pharmaceutical ingredients, exist in water in both the nonionic (mABA) and zwitterionic (mABA±) forms. However, the constituent molecules of the polymorph that crystallizes from aqueous solutions are zwitterionic. This study reports atomistic simulations of the events surrounding the ear...

We describe here the first example of the synthesis of 4-arm star poly(acrylic acid) for use as a water-soluble drag reducing agent, by applying Cu(0)-mediated polymerization technique. High molecular weight 4-arm star poly(tert-butyl acrylate) (Mn = 3.0-9.0 x 10 5 g mol -1 ) was first synthesized using 4,4’-oxybis(3,3-bis(2-bromopropionate)butane as an initiator and a simple Cu(0)/TREN catalys...

The feeding of p-aminobenzoic or cr-amino-y-phenylbutyric acid to rats results in the excretion of acetylaminobenzoic or acetylphenylaminobutyric acid in the urine. Simultaneous feeding of isotopically labeled compounds such as acetic or pyruvic acid (1, 2), Dor L-alanine (3), Dor L-serine (4), or an acetylaminol acid (5) gives rise to labeled acetyl groups. Whereas most combinations of acetyl ...

OxymaPure (ethyl 2-cyano-2-(hydroxyimino)acetate) was tested as an additive for use in the carbodiimide (DIC) approach for the synthesis of a novel series of α-ketoamide derivatives (4-[2-(2-acetylaminophenyl)-2-oxo-acetylamino]benzoyl amino acid ester derivatives). OxymaPure showed clear superiority to HOBt/DIC or carbodiimide alone in terms of purity and yield. The title compounds were synthe...

The kinetics of p-aminobenzoic acid oxidation catalyzed by horseradish peroxidase Compounds I and II was investigated intensively as a function of pH at 25 degrees in aqueous solutions of ionic strength 0.11. All of the rate data were collected from single turnover experiments involving reactions of a single enzyme compound. In reactions of both compounds, deviations from first order behavior w...