This review summarizes an illustrative set of data from our research on the reconstruction of structurally complex protein surfaces, i.e. those that fail to be mimicked properly by linear peptides. In the past 5 years, our newly developed CLIPS TM technology has proven an extremely valuable tool for 1) binding site mapping of therapeutically relevant mAbs, 2) generating hyperimmune sera via imm...

The aim of this study was to explore gender differences in sexual responsiveness to erotic films that had been selected for their differential appeal for men and women. A secondary objective was to identify variables that influence sexual arousal, and explore whether these variables differ for men and women. Fifteen men (mean age = 26) and 17 women (mean age = 24) were presented with 20 heteros...

Introduction Focused training in transthoracic echocardiography enables emergency physicians (EPs) to accurately estimate the left ventricular function. This study aimed to evaluate the efficacy of a brief training program utilizing standardized echocardiography video clips in this regard. Methods A before and after design was used to determine the efficacy of a 1 hour echocardiography traini...

INTRODUCTION A safe closure technique of transluminal access is essential for the widespread application of natural orifice transluminal endoscopic surgery (NOTES). AIM To evaluate the feasibility and effectiveness of a novel single loop-and-clips closure technique (KING closure). MATERIAL AND METHODS An experimental survival study using female laboratory pigs was performed. A gastrotomy wa...

ZnO nano-clips with better monodispersion were prepared successfully using zinc acetate hydrate (Zn(OAc)2·nH2O) as Zn source and ethylene glycol (EG) as solvent by a simple solution-based route-polyol process. The effect of solution concentration on the formation of ZnO nano-clips has been investigated deeply. We first prove that the 0.01 M Zn(OAc)2·nH2O can react with EG without added water or...

A basic question in vision research regards where people look in complex scenes and how this influences their performance in various tasks. Previous studies with static images have demonstrated a close link between where people look and what they remember. Here, we examined the pattern of eye movements when participants watched neutral and emotional clips from Hollywood-style movies. Participan...

BACKGROUND AND OBJECTIVES Laparoscopic appendectomy remains one of the most common emergency general surgical procedures in the United States. In an era of increasing focus on costs in medical care, we sought to evaluate the use of polymeric clips to secure the appendiceal base during laparoscopic appendectomy. METHODS We performed a prospective cohort study of patients undergoing laparoscopi...

PURPOSE This study aimed to compare the difference in mechanical behavior between two types of female-part clips of the Stress-Free Implant Bar (SFI-Bar) system during simulation of insertion-removal cycles. MATERIALS AND METHODS A total of 10 samples simulating SFI-Bar-attachment-retained implant overdentures were fabricated and randomly divided into two groups (n = 5). One group used E-clip...

This paper presents the system used by CLIPS-IMAG to perform the Shot Boundary Detection (SBD) task of the Video track of the TREC-10 conference. Cut detection is performed by computing image di erence after motion compensation. Dissolve detection is performed by the comparison of the norm over the whole image of the rst and second temporal derivatives. An output lter is added in order to clean...

Using a novel approach, we examine which cues in a fingerspelling stream, namely holds or transitions, allow for more successful comprehension by students learning American Sign Language (ASL). Sixteen university-level ASL students participated in this study. They were shown video clips of a native signer fingerspelling common English words. Clips were modified in the following ways: all were s...