Microencapsulation is one of the novel methods for retarding drug release from dosage forms and minimizing the adverse effects thereby increasing the patient compliance. Microspheres form homogeneous, monolithic particles which improve the treatment by providing localization of the drug at the site of action and by prolonging the drug release. The objective of the present study was to formulate...

The objective of this investigation was to develop the hollow microspheres as a new dosage form of floating drug delivery system with prolonged stomach retention time. Hollow microspheres containing ranitidine hydrochloride were prepared by solvent evaporation method using Eudragit RLPO dissolved in a mixture of dichloromethane and ethanol. The maximum yield and drug loading amount of hollow mi...

BACKGROUND Microencapsulation is a useful method to prolong a drug release from dosage forms and to reduce its adverse effect (1) among various available methods. The microencapsulation of hydrophilic active ingredients requires the use of a polar dispersing phase such as a mineral oil. Acetone/paraffin systems are conventionally used. OBJECTIVES The current study aimed to investigate two dif...

Inhalation Ciprofloxacin HCl microspheres were formulated with combination of alginate and kappa carrageenan a total 1% (F1), 1.5% (F2), 2% (F3). Aim this research is to examine effect polymer concentration on characteristics, release, lung deposition microspheres. Microspheres characterized including loading, efficiency, yield, size, moisture content, mucoadhesivity, release. Deposition was st...

Molecularly imprinted polymer microspheres were synthesized by Pickering emulsion polymerization. Fluorescence spectroscopic investigations provided insights into the template recognition in water.

Porous polydivinyl benzene (PDVB) microspheres of narrow size distribution were formed by a single-step swelling process of template uniform polystyrene microspheres with divinyl benzene (DVB), followed by polymerization of the DVB within the swollen template microspheres. The PDVB porous particles were then formed by dissolution of the template polystyrene polymer. Unique "cauliflower-like" Zn...

Interpenetrating polymer network of cross-linked blend microspheres for controlled release Acebutolol HClP. Ramakrishna, B. Mallikarjuna, A. Chandra Babu, P. Sudhakar, K. Chowdoji Rao, M.C.S. Subha

Interpenetrating polymer network of cross-linked blend microspheres for controlled release Acebutolol HClP. Ramakrishna, B. Mallikarjuna, A. Chandra Babu, P. Sudhakar, K. Chowdoji Rao, M.C.S. Subha

Front Cover: In article number 2100022 by Tugrul Cem Bicak, a new method, namely “Type-II photoinitiated precipitation polymerisation”, is described for the synthesis and functionalisation of highly crosslinked microspheres in one step. Using this click functionality introduced to particles at room temperature UV irradiation. A pyrene group then attached onto CuAAC reaction confirm presence acc...

A 4-week sustained release risperidone biodegradable poly(D,L-lactide-co-glycolide) (PLGA) microsphere for the therapy of schizophrenia, the effects of formulation parameters on encapsulation efficiency and release behavior were studied. The risperidone PLGA microspheres were prepared by O/W solvent evaporation method and characterized by HPLC, SEM, laser particle size analysis, GC and HPLC-MS....