نتایج جستجو برای: polymersome

تعداد نتایج: 167  

Journal: :Chemical communications 2010
Min Sang Kim Doo Sung Lee

Novel biodegradable and pH-sensitive polymersomes prepared from poly(ethylene glycol) and poly(d,l-lactide) grafted poly(beta-amino ester) exhibit pH dependent permeability on hydrophilic solutes of which permeability is determined by the packing state of poly(d,l-lactide) membrane followed by ionization of poly(beta-amino ester) inducing loosely packed membrane formation from well-ordered pack...

2017
Xiaohui Duan Liejing Lu Yong Wang Fang Zhang Jiaji Mao Minghui Cao Bingling Lin Xiang Zhang Xintao Shuai Jun Shen

Understanding the long-term fate and potential mechanisms of mesenchymal stem cells (MSCs) after transplantation is essential for improving functional benefits of stem cell-based stroke treatment. Magnetic resonance imaging (MRI) is considered an attractive and clinically translatable tool for longitudinal tracking of stem cells, but certain controversies have arisen in this regard. In this stu...

Journal: :Soft matter 2017
Nestor Lopez Mora Yue Gao M Gertrude Gutierrez Justin Peruzzi Ivan Bakker Ruud J R W Peters Bianka Siewert Sylvestre Bonnet Roxanne E Kieltyka Jan C M van Hest Noah Malmstadt Alexander Kros

Giant Unilamellar Vesicles (GUVs) prepared from phospholipids are becoming popular membrane model systems for use in biophysical studies. The quality, size and yield of GUVs depend on the preparation method used to obtain them. In this study, hydrogels consisting of dextran polymers crosslinked by poly(ethylene glycol) (DexPEG) were used as hydrophilic frameworks for the preparation of vesicle ...

2012
Zhiqing Pang Huile Gao Jun Chen Shun Shen Bo Zhang Jinfeng Ren Liangran Guo Yong Qian Xinguo Jiang Heng Mei

BACKGROUND A novel brain drug delivery system using cationic bovine serum albumin (CBSA)-conjugated biodegradable polymersomes (CBSA-PO) was prepared, and its intracellular delivery mechanism and brain delivery kinetics were evaluated. METHODS AND RESULTS Biodegradable poly(ethylene glycol)-poly(ɛ-caprolactone) (PEG-PCL) was used to prepare the polymersomes, and thiolated CBSA was conjugated ...

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