A NUMBER of bone diseases may affect the orbital bones decreasing the orbital volume and narrowing the optic canal, giving rise to unilateral exophthalmos and usually optic atrophy, simulating clinically an orbital tumour. Among such diseases are osteitis deformans (Paget, 1876); leontiasis ossea (Virchow, 1896); osteopetrosis (Albers-Schonberg, 1904), and the generalized and localized osteitis...

Fibrous dysplasia (FD) is a rare bone disorder caused by mutations of the GNAS gene, which are also identified in malignancies. We explored the potential relationship between breast cancer and fibrous dysplasia in two fibrous dysplasia cohorts from the Netherlands and the United States. Data on fibrous dysplasia and breast cancer diagnosis were retrieved from hospital records of 134 (Netherland...

INTRODUCTION Paget's disease of bone (PDB) is a disease of elderly characterized by disorganized bone remodeling. Development of secondary neoplasm in PDB is a known but rare phenomenon. Development of giant cell tumor in PDB (GCT-PDB) is extremely rare, and little is known about its etiopathogenesis and management. We present a case report of such a development with a review of the literature ...

INTRODUCTION For children ages 1-14, 21.6% of drowning cases involve swimming, wading, or playing in natural bodies of water, such as rivers and lakes. Personal flotation devices (PFDs) are believed to be an effective prevention measure. We measure compliance with city and county ordinances, publicized but not actively enforced, requiring that PFDs be worn by children accessing public bodies of...