Abstract. Let δ(P) be the δ-vector of a reflexive polytope P ⊂ R of dimension d and δ(P) the δ-vector of the dual polytope P ⊂ R. In general, δ(P) = δ(P) does not hold. In this paper, we give a higher-dimensional construction of a reflexive polytope whose δ-vector equals the δ-vector of the dual polytope. In particular, we consider the case that the reflexive polytope and the dual polytope are ...

Previously, we demonstrated that an experimental smallpox DNA vaccine comprised of four vaccinia virus genes (4pox) administered by gene gun elicited protective immunity in mice challenged with vaccinia virus, and in nonhuman primates challenged with monkeypox virus (Hooper JW, et al. Smallpox DNA vaccine protects nonhuman primates against lethal monkeypox. J Virol 2004;78:4433-43). Here, we re...

results cloning and subcloning of the flic gene were confirmed by colony pcr, restriction enzymes digestion and dna sequencing of the recombinant plasmids pprime-flic and pvax-flic. the expression of flagellin protein in eukaryotic cells was approved by immunofluorescence assay (ifa), western blotting analysis and the reverse transcriptase polymerase chain reaction (rt-pcr) method. conclusions t...

In this paper we define a combinatorial object called a pedigree, and study the corresponding polytope, called the pedigree polytope. Pedigrees are in one-to-one correspondence with the Hamiltonian cycles on Kn. Interestingly, the pedigree polytope seems to differ from the standard tour polytope, Qn with respect to the complexity of testing whether two given vertices of the polytope are nonadja...

background and objective: although hepatitis b vaccine immunogenicity is high, certain risk factors such as age, tobacco consumption, obesity and genetic background have been associated with low responsiveness to hbv vaccine. we aimed to evaluate the role of occult hepatitis b virus (hbv) infection in non-responder adults to hbv vaccine in a low endemic area for hbv. material and methods : a to...

The shape of any facet of a 3-polytope can be preassigned. That is, given any 3-polytope P a facet F of P and a polygon F’ with the same number of sides as F, there is an isomorphic 3-polytope P’ such that F is a facet of P’ and the isomorphism takes F onto F (see [ 21). It is also known that given any simple circuit C in the graph of a 3-polytope P, there is an isomorphic 3-polytope P’ such th...

brucellosis is an infectious disease with high impact on innate immune responses which is induced partly by its dna. in the present study the potential differences of wild type and patients isolates versus attenuated vaccine strains in terms of cytokines, ros and no induction on murine splenocytes and peritoneal macrophages were investigated. this panel varied in base composition and included d...

The therapeutic effects of both cytokine-secreting tumor vaccine and DNA vaccine were studied using mouse MBT-2 bladder cancer cells as a model. Cytokine-secreting MBT-2 cells were obtained by infecting cells with retroviral particles containing interleukin (IL) 2-, IL-4-, or granulocyte-macrophage colony-stimulating factor (GM-CSF)-expression vector. The MBT-2-IL-2 cells were not tumorigenic i...