BACKGROUND Despite extensive progress in IVF techniques, one of the most difficult problems is the variability in the response to controlled ovarian hyperstimulation (COH). Recent studies show the effects of individual genetic variability on COH outcome. OBJECTIVE To evaluate the correlation between LHβ G1502A polymorphisms in exon 3 of the LH gene and ovarian response to COH. MATERIALS AND...

background hepatitis b virus (hbv) is a major cause of chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma (hcc). hb vaccination is an essential step in the prevention of the disease and its consequent complications. objectives immune status of medical personnel in teaching hospitals of khuzestan is not well known. since these personnel are usually at risk of needle stick and other...

OBJECTIVES/HYPOTHESIS In order to make possible organ preservation, since 2007 our hospital has performed induction chemotherapy (ICT) with cisplatin and 5-fluorouracil (PF) for hypopharyngeal cancer as chemoselection, followed by alternating chemoradiotherapy (ACRT) with docetaxel, cisplatin, and 5-fluorouracil in (TPF) good responders and curative surgery was used in poor responders. METHOD...

AIM The aim of the study was to investigate the association between follicle-stimulating hormone receptor (FSHR) gene polymorphism at Position 680 and the outcomes of controlled ovarian hyperstimulation for in vitro fertilization and embryo transfer (IVF-ET) in infertile women. MATERIALS AND METHODS One hundred and eight patients under 35 years of age who underwent IVF-ET procedures were incl...

BACKGROUND It would be helpful if patients with asthma who require admission to hospital for an acute attack could be identified. METHODS The relation between the severity of an attack of asthma as determined by admission assessment and the eventual outcome was studied in 52 asthmatic patients aged 14 to 44 years and admitted to an asthma emergency room. The patient's history, including medic...

BACKGROUND Treatment response to systemic corticosteroid in asthmatic children is heterogeneous and may be mediated by epigenetic mechanism(s). We aim to identify DNA methylation (DNAm) changes responsive to steroid, and DNAm biomarkers that distinguish treatment response. MATERIALS AND METHODS We followed 33 children (ages 5-18) presenting to the Emergency Department (ED) for asthma exacerba...

INTRODUCTION To identify markers and mechanisms of resistance to adalimumab therapy, we studied global gene expression profiles in synovial tissue specimens obtained from severe rheumatoid arthritis (RA) patients before and after initiation of treatment. METHODS Paired synovial biopsies were obtained from the affected knee of 25 DMARD (disease-modifying antirheumatic drug)-resistant RA patien...

Background: Assessment of AMH cut-off levels in serum and in follicle fluid (FF) for patients with (group 2, n=34) and without (group1, n= 96) endocrinological risk factors, such as ovarian hyperstimulation syndrome (OHSS) and polycystic ovary syndrome (PCOS), is clinically useful in optimising the treatment protocol. Materials and Methods: AMH was analysed in serum and FF of 130 infertile pati...