A 49-year-old healthy Caucasian woman presented with a sudden change in a lesion on her abdomen. At the time of our consultation, we observed a pigmented papular lesion, 1.5 cm in diameter, surrounded by an incomplete whitish halo with two dark rounded blotches at its top (Figure 1a). The patient had a fair skin phototype and chronic photoaging, characterized by atrophic skin, wrinkling, and di...

Benign eccrine poroma arises from the intraepidermal portion of the eccrine gland duct. Malignant transformation is rare and should be suspected when these lesions present with pain, bleeding or itching. We report a 44-year-old male patient who presented primarily with a lesion diagnostic of benign eccrine poroma of the right foot sole with no clear evidence of malignancy, which was incompletel...

Porokeratotic Variant of Lichen Planus: Lichen planus (LP) is a well-known dermatologic disorder with various different clinical presentations. We present a case of patient who was found to have porokeratotic lichen planus, a previously unreported variant of LP.

BACKGROUND Eccrine porocarcinoma is an uncommon neoplasm of the intra-epidermal sweat gland duct. PATIENTS AND METHODS A case of eccrine porocarcinoma in a female renal transplant patient aged 45 years is described with a review of pertinent literature. RESULTS The primary tumour was highly pleomorphic. In places large and small cells merged and focally the former component infiltrated the ...

Hidroacanthoma simplex is a rare intraepidermal neoplasia that arises from the acrosyringial portion of the eccrine duct. Malignant transformation of hidroacanthoma simplex is reported in the literature and the treatment is performed with wide excision or Mohs micrographic surgery. We report the first case successfully treated with cryosurgery with a long-term follow up.

Melanocytic skin tumors are caused by nevus cells, epidermal melanocytes and dermal melanocytes. The aim of the study was to detect the positivity of Demodex spp. in biopsy specimens of skin diagnosed as nevus. In this retrospective study, the specimens obtained from 110 patients diagnosed with nevus and stained by hematoxylin & eosin (H&E) method were assessed for Demodex. Statistical analysis...

BACKGROUND Apoptosis is important for maintenance of tissue homeostasis and often dysregulated in cutaneous neoplasms. The apoptosis inhibitor survivin is expressed in melanoma and non-melanoma skin cancers and benign keratinocytic lesions. Its expression has not been studied in melanocytic nevi. OBJECTIVE We determined the expression pattern of survivin in benign melanocytic nevi in comparis...

BACKGROUND Acquired bilateral nevus of Ota-like macules (ABNOM) is a dermal pigmented lesion common in individuals of Oriental origin. The Q-switched Nd:YAG laser (QSNYL) has been used successfully to treat a variety of benign, dermal, pigmented lesions, including nevus of Ota lesions. The similarity between ABNOM and nevus of Ota suggested that QSNYL may also be effective in the former. OBJE...