Objectives. The aim of this study was to establish the reliability of the "chewing" subscale of the OPS-NVI, a novel tool designed to estimate presence and severity of orofacial pain in nonverbal patients. Methods. The OPS-NVI consists of 16 items for observed behavior, classified into four categories and a subjective estimate of pain. Two observers used the OPS-NVI for 237 video clips of peopl...

Vitrification of oocytes has been applied recently for humans, but remains elusive. The microtubules of oocytes are vulnerable to cryoprotectants and thermal changes. Using mouse oocytes, the effects of vitrification in open pulled straws (OPS) were investigated on survival, the meiotic spindle, and chromosomes and compared with conventional straws. Mature oocytes were allocated to four groups ...

Wavelength division multiplexing (WDM) switching has been emerging as the dominant technology in optical networks. In this paper, we study the switching performance of WDM optical packet switch (OPS) equipped with tunable wavelength converter sharing dedicated to each output fiber line under self-similar variable packet length traffic. In this study, we model WDM OPS employing tunable wavelengt...

Myelin, made by oligodendrocytes, is essential for rapid information transfer in the central nervous system. Oligodendrocyte precursors (OPs) receive glutamatergic synaptic input from axons but how this affects their development is unclear. Murine OPs in white matter express AMPA receptor (AMPAR) subunits GluA2, GluA3 and GluA4. We generated mice in which OPs lack both GluA2 and GluA3, or all t...

Road safety is a very important issue in many jurisdictions. Road collisions, which have been identified as a major public health problem by the World Health Organization, are the 11th leading cause of global deaths.1 This problem is being addressed in North America through improved education, enforcement and engineering. Having access to better information systems and tools to support decision...

Optical Packet Switched (OPS) networks are known to suffer from high packet losses due to contentions. Techniques such as fiber delay line (FDL) buffering and wavelength conversion help to relieve contentions to an extent, but are expensive and are therefore used sparingly. This paper explores how electronic edge nodes can condition the traffic entering the OPS network with the objective of uti...

In this paper we present research on applying a domain specific high-level abstractions (HLA) development strategy with the aim to “future-proof“ a key class of high performance computing (HPC) applications that simulate hydrodynamics computations at AWE plc. We build on an existing high-level abstraction framework, OPS, that is being developed for the solution of multi-block structured mesh-ba...

Previous studies of early diabetic retinopathy have shown that oscillatory potential (OP) amplitudes are reduced in many diabetic patients. OP amplitude is believed to be a more sensitive indicator of the development of future retinopathy than b-vvave amplitude of the scotopic electroretinogram (ERG). Because OPs measured to a bright white flash reflect both rod and cone system activity, it is ...

The microcirculation plays a crucial role in the interaction between blood and tissues both in physiological and pathophysiological states. Despite its critical role in numerous diseases including diabetes, hypertension, sepsis or multiple organ failure, methods for direct visualization and quantitative assessment of human microcirculation at the bedside are limited. Orthogonal polarization spe...

Objective: Organophosphorus compounds (OPs) are common causes of poisonings. Atropine and oximes are pharmacological antidotes of OPs. However, because of their adverse effects and insufficient performance, several other compounds have been evaluated as adjuvant therapy. HESA-A is a herbal-marine drug that contains material from Carum carvi (Persian cumin), Penaeus latisculatus...