The effect of variously fluorine-substituted β-methyl-β-nitrostyrenes on their antimicrobial activity was investigated. Their efficacy was determined by minimum inhibition concentration (MIC) in cultures of Gram positive and Gram negative bacteria and a fungus. Highest activity against the Gram negative bacterium, E.coli, was achieved with 4-fluorine-aryl substituted β-methyl-β-nitrostyrenes, w...

Lantibiotics are antimicrobial (methyl)lanthionine-containing peptides produced by various Gram-positive bacteria. The model lantibiotic, nisin, binds lipid II in the cell membrane. Additionally, after binding it can insert into the membrane creating a pore. Nisin can efficiently inhibit the growth of Gram-positive bacteria and resistance is rarely observed. However, the activity of lantibiotic...

conclusions preliminary results indicate that the native iranian actinobacteria could be considered a suitable option for screening of the new antibacterial compounds. molecular research and antibacterial compound extraction against the aforementioned pathogenic strains are also being conducted. results based on the morphological characterization, 35 isolated cases belonged to actinomycetes and...

OBJECTIVE To evaluate methanolic, ethanolic, acetone and aqueous extracts from different parts of Eurycoma longifolia (E. longifolia) (leave, stem, and root) for antibacterial activity against Gram-positive and Gram-negative bacteria and to utilize the leaves and stem parts rather than the root, which is already used for male sexual enhancement in Malaysia. METHODS The study took place in the...

Organic extracts (ethanol, petroleum ether and chloroform) of two medicinal plants Lawsonia inermis L. and Mimosa pudica L. were proven for antibacterial properties against 15 Gram-positive and Gram-negative human pathogenic bacteria. Among the three types of extracts tested, ethanol extract was found to possess maximum antibacterial activity. The diameter of the zone of inhibition of bacterial...

quinazolinone ring system is renown because of its wide spectrum of pharmacological activities due to various substitutions on this ring system. in this study, the minimum inhibitory concentration of the synthesized compounds in our laboratory was determined by micro dilution alamar blue ® assay against six strains of bacteria (three gram-positive and three gram-negative) and three strains of f...

nowadays, uncontrolled and frequent use of antibiotics may cause emergence of microbial resistanceamong pathogenic agents. therefore, the use of new synthetic and natural antimicrobial compounds isinevitable. one source of natural compounds in this respect comes from plants. the purpose of this study was to examine the antibacterial effects of peel extracts from sour and sweet pomegranate. meth...