PURPOSE To present the MR and histopathologic findings in five children with meningiomas. METHODS Five children aged 3 months to 16 years with pathologically proved meningiomas underwent preoperative contrast enhanced MR. Tissue in four patients was sent for chromosomal analysis in addition to routine histopathologic studies. RESULTS All five tumors were extra-axial, two supratentorial and ...

Atypical and malignant meningiomas are rare. Our aim was to examine the treatment outcomes following surgical resection, and analyze associations between clinical characteristics and overall survival (OS) or relapse free survival (RFS). 102 patients with atypical or malignant meningiomas underwent microsurgical resection between June 2001 and November 2009 were analyzed retrospectively. We comp...

It has been alleged that radioisotope scanning of posterior fossa lesions is of little value (1-8) or at best, difficult (9,10) and frequently unrewarding (11). Some clinics even report the virtual abandonment of posterior fossa scanning (12,13). On the other hand, there are those who maintain that scanning of the posterior fossa is a worthwhile adjunct in the evaluation of lesions in that re g...

Adult survivors of childhood brain tumors are at risk for cognitive performance deficits that require the core cognitive skill of working memory. Our goal was to examine the neural mechanisms underlying working memory performance in survivors. We studied the working memory of adult survivors of pediatric posterior fossa brain tumors using a letter n-back paradigm with varying cognitive workload...

Introduction/Background: Surgery plays a crucial role in the surgical management of posterior fossa tumors children, but maximizing resection while preserving function remains challenging. Along with other tools available to surgeon, intraoperative neuromonitoring aims at improving safety during these complex interventions. This case report highlights real-time surgery and its impact on surgeon...

Isolated fourth ventricles were diagnosed by computed tomography (CT) in 16 children in a 3 year period. They all had had shunting of the lateral ventricles for hydrocephalus, and all needed subsequent shunt revisions. Seven patients without signs of raised intracranial pressure clinically had new posterior fossa signs at different intervals after lateral ventricular shunting. The clinical find...

A patient with a 3-month history of headache refractory to pain medication was admitted. The CT scan and MRI showed evidence of a posterior fossa mass. This was pathologically confirmed as an extra medullary plasmacytoma (EMP). He had a pathologic fracture of the left humerus 7 years ago while the radiologist was unaware at the time of diagnosis. A solitary bone plasmacytoma (SBP) was the cause...

This study evaluated the clinical features, treatment strategies and outcomes of solid hemangioblastomas in 28 patients diagnosed with hypervascular lesions in the posterior fossa. Preoperative embolization of the feeding arteries had limited effects, with only 7 patients benefitting from it for the reduction of intraoperative hemorrhage. The tumor was completely removed in all patients, and 22...

Posterior fossa syndrome is characterized by cerebellar dysfunction, oromotor/oculomotor apraxia, emotional lability and mutism in patients after infratentorial injury. The underlying neuroanatomical substrates of posterior fossa syndrome are unknown, but dentatothalamocortical tracts have been implicated. We used pre- and postoperative neuroimaging to investigate proximal dentatothalamocortica...