Posterior vitreous detachment is a fairly common condition in elderly people. Tractions exerted by the detached vitreous on the retina may result in retinal tears and detachments. We studied how these tractions can arise from saccadic eye movements. Numerical simulations have been performed on a two-dimensional model of the vitreous chamber within a rigid spherical sclera, subjected to prescrib...

Medical records of a 46‐year‐old woman with bilateral myopia, gyrate atrophy, and history of night blindness were reviewed. The patient underwent macular hole surgery in the left eye 3 years back. The surgery consisted of pars plana vitrectomy (PPV), induction of posterior vitreous detachment (PVD), internal limiting membrane (ILM) peeling, and fluid‐air exchange. She had serum ornithine level ...

AIMS To investigate the ultrastructure of the vitreoretinal interface following plasmin induced posterior vitreous detachment. METHODS Plasmin (1 or 2 U/0.1 ml) was injected into the vitreous cavity of 24 eyes of freshly slaughtered pigs. The 24 fellow eyes received calcium-free and magnesium-free PBS and served as a control. After incubation at 37 degrees C for 30 and 60 minutes, the globes ...

MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression by post-transcriptional inhibition of mRNA translation. Dysregulation of miRNAs, including circulating miRNAs, has been reported to play an important role in the development of various diseases, including fibrotic diseases. Aberrant expression of miRNAs in the vitreous humor of vitreoretinal diseased eyes has been reporte...

PURPOSE Floaters impact vision but the mechanism is unknown. We hypothesize that floaters reduce contrast sensitivity function, which can be normalized by vitrectomy, and that minimally invasive vitrectomy will have lower incidences of retinal tears (reported at 30%) and cataracts (50-76%). METHODS Seventy-six eyes (34 phakic) with floaters were evaluated in 2 separate studies. Floater etiolo...

OBJECTIVE We report a 50-year-old female patient with a stage 2 idiopathic macular hole that closed spontaneously. METHOD The case is presented on the basis of an observational case report. RESULTS The stage 2 idiopathic macular hole closed spontaneously in 6 weeks with a lamellar defect in the outer retina due to the formation of the bridging retinal tissue, but without any evidence of the...

Inducing posterior vitreous detachment (PVD), as well as eliminating the traction forces affecting the central retina, are two of the main objectives of vitreous-retina surgery in the treatment of a number of pathologies such as refractory diabetic macular edema or macular hole. This type of surgery is not risk-free because, in addition to being technically complicated in some cases, even for e...

BACKGROUND To describe clinical outcomes in a series of patients with tractional cystoid macular edema, a variant of vitreomacular traction syndrome. METHODS Twelve consecutive patients (15 eyes) with tractional cystoid macular edema of maximum diameter of ≤550 μm and presenting corrected-distance visual acuity of ≤0.3 (Snellen ≥20/40) were studied. Each patient underwent ophthalmic examinati...

In this report, we consider retinal detachment in the eye, which happens when the retina comes away from the choroid. This condition is often treated by removing the vitreous humour from the eye (vitrectomy) and spot-welding the retina back on to the choroid. After this, the vitreous body is refilled with saline or silicone oil. The vitreous humour is a viscoelastic material, with a very high e...