INTRODUCTION Pulsatile hyperglycaemia resulting in oxidative stress may play an important role in the development of macrovascular complications. We investigated the effects of sustained vs. pulsatile hyperglycaemia in insulin resistant rats on markers of oxidative stress, enzyme expression and glucose metabolism in liver and aorta. We hypothesized that liver's ability to regulate the glucose h...

BACKGROUND Stress hyperglycaemia is common in the intensive care unit (ICU) setting and has been related to a worst outcome. OBJECTIVE The objective was to characterize the association of glucoregulatory hormones, mainly incretins, with the levels of glycaemia, and its relationship with outcome in ICU patients. METHODS We prospectively studied 60 patients. Stress hyperglycaemia was diagnose...

Diabetic ulcer refers to a complication of chronic hyperglycaemia. When treating hyperglycaemia, it is necessary well and immediately monitor the average level glucose, i.e. glycated albumin (GA) value. This study investigated correlation between GA values improvement diabetic ulcers. A clinical, cross-sectional study. Thirty patients with Foot Ulcer (DFU) were involved as subjects this they se...

Occasionally, malaria may present with unusual signs and symptoms. We report a case of an uncommon presentation of Plasmodium falciparum infection in a 59-year-old Ethiopian immigrant, which initially presented with hyperglycaemia and multiple organ dysfunction syndrome (MODS). Reports of unusual presentations of malaria are few and cases of severe malaria with hyperglycaemia are rarely describ...

AIMS The prevalence of post-challenge hyperglycaemia in coronary patients is high. Until now, it is unclear whether post-challenge hyperglycaemia is associated with an increased risk for future macrovascular events in this clinically important patient population. METHODS AND RESULTS We enrolled 1040 patients undergoing coronary angiography for the evaluation of suspected or established corona...

BACKGROUND Patients with diabetes have an increased risk for allograft rejection, possibly related to peri-operative hyperglycaemia. Hyperglycaemia is also common following transplantation in patients without diabetes. We hypothesise that exposure of allograft tissue to hyperglycaemia could influence the risk for rejection in any patient with high sugars. To investigate the relationship of peri...

 Copyright 2003 Journal of Postgraduate Medicine. Online full text at http://www.jpgmonline.com The issue of hyperglycaemia in patients with acute stress continues to generate a lot of debate. Up to 50% of patients with stroke are reported to have hyperglycaemia at admission to the hospital and up to 25% of those admitted to the hospital with stroke may report history of diabetes mellitus. Thi...