نتایج جستجو برای: potassium channelopathy
تعداد نتایج: 77926 فیلتر نتایج به سال:
atp-sensitive potassium (katp) channel openers have a relaxation effect due to the lower cellular membrane potential and inhibit calcium influx. there has been considerable interest in exploring katp channel openers in the treatment of various diseases such as cardiovascular, cerebrovascular, and urinary system disease and premature labor. the purpose of this study was to synthesize 3,3,6,6-tet...
BACKGROUND/AIMS SCN5A encodes the cardiac-specific Na(V)1.5 sodium channel, and Brugada syndrome is a cardiac conduction disorder associated with sodium channel α-subunit (SCN5A) mutation. The SCN5A-encoded Na(V)1.5 channel is also found on gastrointestinal smooth muscle and interstitial cells of Cajal. We investigated the relationship between functional dyspepsia (FD) and SCN5A mutation to eva...
Classically, genetic testing has been reserved for individuals with a reasonable pre-test probability of disease. However, the use commercial preventative (PGT) to identify asymptomatic at risk various heritable disorders, most commonly those linked cancer and cardiovascular disease, increased significantly. To describe our experience regarding incidentally discovered pathogenic (P)/likely (LP)...
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