نتایج جستجو برای: pr3 doped cofe2o4
تعداد نتایج: 49830 فیلتر نتایج به سال:
پروتئیناز 3 یک نوتروفیل سرین پروتناز و به عنوان یک اتو آنتی نوتروفیل سیتوپلاسمیک اتوآنتی بادیها که در سرم افراد با بیماری گرانولوماتوز وگنر دیده می شود، می باشد. فرم خالص شده این پروتئیناز جهت مطالعه این بیماران بسیار حائز اهمیت است . در این تحقیق دو نوع pr3 انسانی بصورت نوترکیب تهیه شد. بخشی از pr3cdna که فرم فعال راکد می کند انتخاب و با انجام واکنش نسخه برداری معکوس و واکنش زنجیری پیوسته بر ر...
We report on the coupling between ferroelectric and magnetic order parameters in a nanostructured BaTiO3-CoFe2O4 ferroelectromagnet. This facilitates the interconversion of energies stored in electric and magnetic fields and plays an important role in many devices, including transducers, field sensors, etc. Such nanostructures were deposited on single-crystal SrTiO3 (001) substrates by pulsed l...
The evolution of size and size distribution during hydrothermal synthesis of nanocrystalline CoFe2O4 has been studied by in situ synchrotron powder X-ray diffraction (PXRD). Varying synthesis temperature or [OH(-)] concentration in the precursor proves to have no significant effect on the final volume-weighted nanocrystallite sizes (∼12 nm) of CoFe2O4. However, analysis by whole powder pattern ...
Anti-neutrophil cytoplasmic antibodies (ANCA) targeting proteinase 3 (PR3) possess a high sensitivity and specificity for Wegener's granulomatosis. Due to their capacity of directly activating neutrophils, a pathogenetic role for these autoantibodies has been proposed. We investigated the impact of subthreshold concentrations of monoclonal anti-PR3 antibodies (anti-PR3; 0.1 microg/mL) on neutro...
Proteinase 3 (PR3), which is also called myeloblastin, the target autoantigen for antineutrophil cytoplasmic antibodies (ANCA) in Wegener’s granulomatosis, is a serine proteinase stored in azurophil granules of human neutrophils. We have previously shown that, in contrast to elastase or myeloperoxidase, PR3 is also expressed at the plasma membrane of a subset of unactivated neutrophils and that...
Proteinase 3 (PR3), which is also called myeloblastin, the target autoantigen for antineutrophil cytoplasmic antibodies (ANCA) in Wegener's granulomatosis, is a serine proteinase stored in azurophil granules of human neutrophils. We have previously shown that, in contrast to elastase or myeloperoxidase, PR3 is also expressed at the plasma membrane of a subset of unactivated neutrophils and that...
BACKGROUND Anti-neutrophil cytoplasmic antibodies (ANCA) directed against proteinase 3 (PR3) are highly specific for Wegener's granulomatosis (WG). Evidence for a pivotal role of PR3-ANCA in the induction of vasculitis has been demonstrated. B cell clusters have been observed within endonasal biopsy specimens. OBJECTIVES To determine whether B cell selection and maturation take place in granu...
BACKGROUND AND AIMS The only recognized biomarker for primary sclerosing cholangitis (PSC) is atypical anti-neutrophil cytoplasmic antibodies (aANCA), which, in addition to having low sensitivity and specificity, is an indirect immunofluorescence (IIF) test lacking the advantages of high throughput and objectivity. Recent reports have shown that antibodies to proteinase-3 (PR3-ANCA) might add d...
Approximately single-domain-sized 9-, 13-, and 16-nm CoFe2O4 nanoparticles are synthesized using the thermal decomposition of a metal-organic salt. By means of dilution and reduction, the concentration, moment, and anisotropy of nanoparticles are changed and their influence on the magnetic properties is investigated. The relation of M r/M s ∝ 1/lgH dip is observed, where M r/M s is the remanenc...
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