While chemoresistance in primary tumors is well-studied, much less is known about the influence of systemic chemotherapy on the development of drug resistance at metastatic sites. In this work, we use a hybrid spatial model of tumor response to a DNA damaging drug to study how the development of chemoresistance in micrometastases depends on the drug dosing schedule. We separately consider cell ...

Software Pipelining is a loop scheduling technique that extracts parallelism from loops by overlapping the execution of several consecutive iterations. Prior scheduling research has focused on achieving minimal execution time, without regarding register requirements Unidirectional strategies (top-down or bottom-up) tend to stretch operand lifetimes because they schedule some operations too earl...

Workload construction methodologies for multiprogram experiments are more complicated than those for single-program experiments. Fixed-workload methodologies pre-select samples from each program and use these in every experiment. They enable direct comparisons between experiments, but may also yield runs of which significant portions are spent executing only the slowest program(s). Variable-wor...

This paper presents a new scheduling algorithm, called Real-Time HCCA (RTH), devised to support Quality of Service (QoS) at the flow level in an IEEE 802.11e network using the Hybrid Coordinator Function (HCF) Controlled Channel Access (HCCA) function. RTH separates online activities which take place at the frame transmission timescale, from offline activities which take place at the flow lifet...

In this paper, a novel sub-channel based uplink Orthogonal Frequency Domain Multiple Access (OFDMA) random access scheme is proposed. In the next generation Wireless Local Area Network (WLAN), OFDMA was adopted in order to enhance throughput performance. OFDMA can be used for both downlink and uplink. In order to utilize OFDMA for uplink, AP needs to schedule stations’ packet transmission. In o...

OBJECTIVES This study aims to identify current blood transfusion requirements in elective open abdominal aortic aneurysm repair and to compare this to an existing maximum surgical blood order schedule. METHODS We retrospectively identified patients who underwent elective open abdominal aortic aneurysm repair over a 40-month period in our institution. Pre-operative number of units cross-matche...

Software Pipelining is a loop scheduling technique that extracts parallelism from loops by overlapping the execution of several consecutive iterations. Prior scheduling research has focused on achieving minimal execution time, without regarding register requirements Unidirectional strategies (top-down or bottom-up) tend to stretch operand lifetimes because they schedule some operations too earl...

An iconic building linking Bangladesh's southwest to its northern and eastern areas is the Padma bridge, which spans third-largest river in world with a complicated topology. By boosting production, employment, transportation, national regional economy, this multipurpose bridge projected boost GDP growth by 1.2%. This study's primary goal pinpoint greatest challenges encountered during Bridge's...