OBJECTIVE To study the association between peri-conceptional A1C and serious adverse pregnancy outcome (congenital malformations and perinatal mortality). RESEARCH DESIGN AND METHODS Prospective data were collected in 933 singleton pregnancies complicated by type 1 diabetes. RESULTS The risk of serious adverse outcome at different A1C levels was compared with the background population. The ...

Context Placenta-mediated pregnancy complications, ranging from miscarriage to growth restriction and pre-eclampsia, collectively affect more than 25% of pregnancies. While the aetiology of pregnancy complications is heterogeneous, it is plausible that common processes such as inflammation and activation of the coagulation system play key roles. Therefore, antithrombotic treatments, specificall...

ARTICLES Endocrinology Acarbose reduces elevated testosterone serum concentrations in hyperinsulinaemic premenopausal women: a pilot study Preconceptional and gestations! evaluation of insulin secretion in patients with polycystic ovary syndrome Nuclear maturity and oocyte morphology after stimulation with highly purified follicle stimulating hormone compared to human menopause! gonadotrophin V...

Transplacental transmission of Japanese encephalitis virus (JEV) has been demonstrated in consecutive pregnancies of mice. Pregnant mice inoculated intraperitoneally with JEV transmit the virus to the foetus. When such female mice were mated again after 6 months, the virus could be isolated from the foetuses of the ensuing pregnancy. The incidence of abortion was increased significantly though ...

Address for Correspondence: Dr. Joseph Abraham, Department of Anatomy, Government Medical College and Hospital, Chandigarh 32, India, 160030. Phone No.: +919041466127. E-Mail: [email protected] Chiari malformations (CM) are named for Hans Chiari, an Austrian pathologist, who first identified type I-III in 1891. This study was conducted on 400 fetuses obtained from department of Obstetrics an...

The importance of lifestyle and dietary habits during pregnancy and breastfeeding, for health of mothers and their offspring, is widely supported by the most recent scientific literature. The consumption of a varied and balanced diet from the preconceptional period is essential to ensure both maternal well-being and pregnancy outcomes. However, the risk of inadequate intakes of specific micronu...