نتایج جستجو برای: preimplantation genetic diagnosis

تعداد نتایج: 1057387  

Journal: :Orphanet Journal of Rare Diseases 2015

Journal: :Canadian Medical Association Journal 2007

2001

Preimplantation Genetic Diagnosis T he opportunity to exclude in-vitro derived embryos with documented genetic abnormalities before the initiation of pregnancy is an attractive means of preventing heritable genetic disease. Currently couples who are carriers of genetic disease have the option of undergoing chorionic villus sampling in the first trimester or amniocentesis in the second trimester...

Journal: :Clinical chemistry 2015
Yanwen Xu Shengpei Chen Xuyang Yin Xiaoting Shen Xiaoyu Pan Fang Chen Hui Jiang Yu Liang Wei Wang Xun Xu Jian Wang Xiuqing Zhang Canquan Zhou Jun Wang

BACKGROUND The embryonic genome, including genotypes and haplotypes, contains all the information for preimplantation genetic diagnosis, representing great potential for mendelian disorder carriers to conceive healthy babies. METHODS We developed a strategy to obtain the full embryonic genome for a β-thalassemia-carrier couple to have a healthy second baby. We carried out sequencing for singl...

2005
Semra Kahraman

Since its first clinical application in early 90s, preimplantation genetic diagnosis (PGD) has became a powerful diagnostic procedure in clinical practice for avoiding the birth of an affected child as well as increasing the assisted reproductive technologies (ART) outcome . The technique involves the screening of preimplantation embryos for chromosomal abnormalities in certain indications such...

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