Background and objective: Several studies have been conducted about Bacterial Vaginosis and its relation with preterm labor that was accompanied with controversial results. The aim of this study was to compare the frequency of Bacterial Vaginosis and common genitourinary infections between term and pre-term pregnancies. Methods: In a case-control study, 249 pregnant women admitted to Shohadyae ...

The present study tested the hypothesis that ERK activation is an essential step in the onset of labor in a rat model of preterm labor. The administration of RU-486, an antiprogesterone agent, to rats induced preterm delivery 22.2 +/- 0.24 h after treatment. Changes in basal signaling events were studied in myometrial tissue from CO(2)-euthanized rats. Rats treated with RU-486 displayed a drama...

The present study tested the hypothesis that ERK activation is an essential step in the onset of labor in a rat model of preterm labor. The administration of RU486, an antiprogesterone agent, to rats induced preterm delivery 22.2±0.24 hrs after treatment. Changes in basal signaling events were studied in myometrial tissue taken from CO2 euthanized rats. Rats treated with RU486 displayed a drama...

Introduction. In Netherlands, the obstetric care system is divided into primary and secondary care by risk level of the pregnancy. We assessed the incidence of preterm birth according to level of care and the association between level of care at time of labor onset and delivery and adverse perinatal outcome. Methods. Singleton pregnancies recorded in Netherlands Perinatal Registry between 1999 ...

BACKGROUND Although several socio-medical risk factors have been identified for preterm labor, there is a gap in understanding the underlying etiology of preterm labor. OBJECTIVES The current study aimed to analyze the relationship pathway of perceived social support, stressful life events, and other psychosocial risk factors during pregnancy with incidence of preterm labor. MATERIALS AND M...

According to the World Health Organization (WHO) recommendation,[1] preterm labor is defined as labor starting earlier than 37 completed weeks (less than 259 days) from the first day of the last menstrual period and the term premature should no longer be used. The term premature was previously defined as a birth weight of less than 2500 gm. Therefore, this will include infants of low birth weig...

The principal difference between term and preterm labor is how they are activated. It has been proposed that term labor results from physiological activation of the common terminal pathway, whereas preterm labor is a pathological condition caused by multiple etiologies that activate one or more of the components of this pathway. Increased uterine contractility at preterm labor results from acti...

OBJECTIVE Visfatin, a novel adipokine with metabolic and immunoregulatory properties, has been implicated in the regulation of fetal growth, as well as in preterm labor. A gap in knowledge is whether spontaneous labor at term is associated with changes in the maternal and fetal concentrations of visfatin. The aim of this study was to determine if the presence of labor at term is associated with...

PURPOSE To compare the clinical benefit and cost-effectiveness of utilizing continuous subcutaneous terbutaline versus oral tocolytics following recurrent preterm labor. DESIGN Retrospective, 1:1 matched cohort. METHODOLOGY From prospectively collected data in a nationwide, perinatal database of women receiving outpatient services, we identified singleton gestations having recurrent preterm...

Normal term and spontaneous preterm births (PTB) are documented to be associated with oxidative stress (OS), and imbalances in the redox system (balance between pro- and antioxidant) have been reported in the maternal-fetal intrauterine compartments. The exact mechanism of labor initiation either at term or preterm by OS is still unclear, and this lack of understanding can partially be blamed f...