the monitoring and reporting of adverse drug reactions (adrs) in hospitals aims to identify and quantify the risks associated with the use of drugs. the present study was performed to characterize the rate and the pattern of adrs, due to cardiovascular drugs and anticoagulants, in a tertiary care teaching hospital. for this purpose, all the patients treated with cardiovascular drugs and anticoa...

Medication constitutes a major clinical intervention that may yield significant benefits for the patients. Yet, it can also cause considerable harm, if inappropriately used/ applied. In the US, adverse drug effects are considered as one of the 10 principal causes of death, which has been estimated to harm at least 1.5 million patients/year, with about 25% of the cases being preventable [1]. Hos...

As the incidence of vaccine preventable diseases has declined, and more new vaccines are marketed, adverse events following immunisation have attracted greater attention from the public and from health care providers. At a population level, post-licensure monitoring of vaccine safety in many countries relies on notifications to passive surveillance systems, such as the Australian Adverse Drug R...

The clinical spectrum of cutaneous adverse drug reactions range from benign, self-limiting reactions to life-threatening conditions. Patients with severe cutaneous adverse drug reactions require longer hospitalisation that cost both the hospital and health care system. Cutaneous adverse drug reactions are common complications of medical therapy. While most are benign and self-limiting after wit...

Purpose: This study aims to investigate preventability criteria of adverse drug reactions (ADRs) involving non-steroidal anti-inflammatory drugs (NSAIDs) by analyzing individual case safety reports (ICSRs) sent through Campania region (Italy) spontaneous reporting system from July 2012 to October 2016. Methods: For all the ICSRs that reported NSAIDs as suspected drug, a trained multidisciplinar...

This study investigated the occurrence and characteristics of adverse drug reactions (ADR) in our hospital and provide references for clinical rational drug use. We collected the 85 case reports of adverse drug reactions in our hospital in 2010 and made retrospective statistical analysis on them. The varieties of anti-infective drugs used are the most used. It also had the highest proportion of...

background : following establishment of iranian adverse drug reaction (adr) monitoring  center  in  1997, adr  committees  were  established  in  all  hospitals  of mazandaran province of iran. clinical pharmacists from mazandaran university of medical sciences have been involved with these committees since 2007. the aim of this study was to compare the results of the pharmacovigilance system b...

introduction: amodiaquine is a partner drug in the artemisinin-based combination therapy artesunate-amodiaquine. reports of the adverse drug reaction known as amodiaquine-associated asthenia are scarce, and this adverse reaction needs to be investigated in detail. this article presents and reviews a case of amodiaquine-associated asthenia. a literature search for the characteristics of this adv...

BACKGROUND It has been claimed that the risk of adverse drug reactions increases with age. However, only limited data exist for disease-group specific risks and none for patients with liver and gastrointestinal diseases. AIMS To determine the incidence and characteristics of adverse drug reactions and the physicians' awareness of adverse drug reactions. METHODS During a 7-month period, a pr...