Refractive errors and primary open-angle glaucoma are common eye conditions in the United States. The identification and quantification of risk factors for primary open-angle glaucoma is critical to understanding and managing the disease process from both individual and public health perspectives. This narrative review was conducted to present the epidemiology of primary open-angle glaucoma and...

OBJECTIVE To determine whether there is a difference in disease severity between familial and sporadic primary open-angle glaucoma (POAG). METHODS A cross-sectional study design compared the distribution of Glaucoma Inheritance Study in Tasmania (GIST) severity scores of patients with genealogically confirmed familial POAG and those with sporadic POAG. The GIST severity scores provide a combi...

We report a retrospective study of 60 eyes from 46 patients all with primary open-angle glaucoma who had a trabeculectomy to one or both eyes. A minimum five-year follow-up was available. The percentage pressure reductions at the one and five years postoperatively is shown. In a subgroup of 50 eyes which had Goldman fields documented at least six-monthly for a minimum of five years postoperativ...

Closed-angle glaucoma is the result of two mechanisms acting either separately or in combination: 1. Pupil block creates a greater pressure in the posterior than in the anterior chamber, pushing the iris on to the cornea. 2. Increased trabecular meshwork outflow in the presence of pupil block creates a lower pressure in the anterior chamber than in the posterior, pulling the iris on to the corn...

A clinical audit was conducted for a 4-year period at the Universiti Kebangsaan Malaysia (UKM) Ophthalmology Department in which 61 eyes of adult patients with primary glaucoma underwent trabeculectomies without antimetabolites. At a 2-year follow-up duration, successful trabeculectomies as defined by intraocular pressure below 20 mm Hg without additional glaucoma medication were 62% for primar...

In order to determine if post-traumatic angle recession is a risk factor for failure of glaucoma filtering surgery independent of age or race, the surgical results of trabeculectomy performed in 35 consecutive patients with angle recession glaucoma were compared with those of 35 matched patients with primary open angle glaucoma. A postoperative intraocular pressure of < or = 21 mm Hg (with or w...

PERIPHERAL iridectomy has become an accepted method of treating closedangle glaucoma. During the last 4 years we have performed this operation on more than seventy eyes and the results have convinced us that this is one of the safest and most successful of all operations for glaucoma provided that the cases are properly selected. It is the ideal operation for early cases of closed-angle glaucom...

AT WHAT stage in its course closed-angle glaucoma may be said to have become chronic is difficult to define. When, however, pathological cupping of the optic disc and visual field loss have occurred in an eye with closedangle glaucoma, the disease may reasonably be said to have reached the chronic stage. The aqueous outflow in such an eye is usually regarded as being permanently impaired by the...

Trabeculectomy surgery has been shown to lower intraocular pressure and is the most commonly performed glaucoma procedure worldwide. However, giving a patient a 'bleb for life' is not without consequences and the failure of trabeculectomy to control IOP in the long term is well documented. In some instances, such as in patients with exfoliative glaucoma or primary angle closure glaucoma, catara...