Background: Sjögren’s syndrome is the second most common systemic autoimmune disease after rheumatoid arthritis, RA, with a prevalence of about 0.5% in the general population. It occurs primarily in perimenopausal women (at a ratio of women to men of 9: 1) Sjögren’s syndrome is characterized by lymphocytic infiltration to exocrine glands. The specific autoantibodies of this syndrome are against...

Uhal, Bruce D., Carlos Ramos, Iravati Joshi, Antonio Bifero, Annie Pardo, and Moises Selman. Cell size, cell cycle, and a-smooth muscle actin expression by primary human lung fibroblasts. Am. J. Physiol. 275 (Lung Cell. Mol. Physiol. 19): L998–L1005, 1998.—Primary human lung fibroblasts were separated into small ( group I), intermediate ( group II), and large ( group III) subpopulations by unit...

In erosion and sedimentation problems, estimating the range of significant stream flows to include when computing sediment transport can prove challenging in ungauged or under-gauged basins. This paper describes an event-based model incorporating a geomorphologic instantaneous unit hydrograph and stochastic descriptions of peak flows and frequency of storm events from nearby reference watershed...

The isolation and sorting of cells has become an increasingly important step in chemical and biological analyses. As a unit operation in more complex analyses, isolating a phenotypically pure cell population from a heterogeneous sample presents unique challenges. Microfluidic systems are ideal platforms for performing cell separations, enabling integration with other techniques and enhancing tr...

Continuous sedimentation of solid particles in a liquid takes place in a clarifierthickener unit, which has one feed inlet and two outlets. The process can be modeled by a nonlinear scalar conservation law with point source and discontinuous flux function. This paper presents existence and uniqueness results in the case of varying cross-sectional area and a complete classification of the steady...

A dispersed-ozone flotation (DOF) separator was devised for a pilot study of tertiary wastewater treatment for re-use purposes. As a compact device combining coagulation, ozonation and flotation in an integrated unit, the DOF separator achieved a very high removal of SS, TOC, UV254 and colour, as well as effective inactivation of coliform and total bacteria within a short hydraulic retention ti...

We describe a method leading to the formation of closed circles of rDNA starting from total DNA of Xenopus laevis. Linear DNA molecules were digested with exonuclease 3 and self-annealed. Open circles were enriched and covalently closed by the simultaneous use of polynucleotide kinase, DNA polymerase and polynucleotide ligase. Closed circles of rDNA1 were shown to be alkali-resistant, to have h...

The armored layer is crucial for protecting the riverbed. bed of river a movable material that protects below surface layer. This study aimed to develop formulas estimate thickness mobile armor with noncohesive materials and establish correlation between flow velocity shear stress under conditions erosion sedimentation. research methods included field measurements, laboratory tests, numerical s...