This paper takes the surrounding rock of deep tunnel as research object and considers action mechanism under influence seepage. Based on Mohr-Coulomb criterion, stress buried is analyzed by a convergence constraint method. elastic-plastic solution, nonlinear solution interaction between lining structure considering effect seepage force proposed, radius plastic zone obtained. The relationship di...

In this paper, the discrete method of eigenvectors of covariance matrix has been used to weight minimization of steel frame structures. Eigenvectors of Covariance Matrix (ECM) algorithm is a robust and iterative method for solving optimization problems and is inspired by the CMA-ES method. Both of these methods use covariance matrix in the optimization process, but the covariance matrix calcula...

Soft computing analysis of data The Principal Component Analysis (PCA) methodology was applied to display data. PCA is a mathematical linear transformation aimed to scale the data in a three-dimensional uncorrelated space, in order to display statistically meaningful differences among the original variables while retaining as much as possible of the variance present in the original dataset. PCA...

This study clarifies the seepage characteristics of complex fractured pressure-sensitive reservoirs, and addresses a common technological problem, that is alteration permeability degree reservoir bed (known to be responsible for changes in direction velocity fluid flows between wells). On basis new equation considers fracture directional effect, an oil-gas-water three-phase mathematical model i...

The water permeability of the kidney collecting duct epithelium is regulated by vasopressin (VP)-induced recycling of water channels between an intracellular vesicular compartment and the plasma membrane of principal cells. To test whether the water channels pass through an acidic endosomal compartment during the endocytic portion of this pathway, we measured ATP-dependent acidification of FITC...

To investigate the anisotropy of coal swelling, this study proposes an effective stress model for saturated, adsorptive fractured porous media by considering gas adsorption induced surface change on solid-fluid interface. The can be used to capture anisotropic swelling combining mechanical properties and link with permeability. Direction dependent fracture compressibility is describe evolution ...

Low-permeability glutenite reservoir pattern deployment and optimization are important for its efficient development. In this paper, taking the in Sha 4 member of Yong1 as an example, numerical simulation method percolation theory used to study influence sediment source in-situ stress direction on well deployment. Then, low-permeability was optimized, finally optimized parameters designed. It i...

BACKGROUND Endothelial cell junctions control blood vessel permeability. Altered permeability can be associated with vascular fragility that leads to vessel weakness and haemorrhage formation. In vivo studies on the function of genes involved in the maintenance of vascular integrity are essential to better understand the molecular basis of diseases linked to permeability defects. Ve-ptp (Vascul...

Measurements have been made of the permeability of the isolated urinary bladder of the toad to a number of small solute molecules, in the presence and absence of vasopressin. Vasopressin has a strikingly specific effect on increasing permeability of the bladder to a group of small, uncharged amides and alcohols while penetration by other small molecules and ions is unaffected. The movement of u...