AIM To evaluate the effect of a high dose vitamin A and E supplementation on corneal re-epithelialisation time, visual acuity and haze following photorefractive keratectomy (PRK). METHODS Two groups of 20 patients who underwent myopic PRK were supplemented with either 25 000 IU retinol palmitate and 230 mg alpha tocopheryl nicotinate or a placebo. Clinical outcomes were evaluated up to 360 da...

Photorefractive keratectomy (PRK) remodels corneal stroma to compensate refractive errors. The removal of epithelium and the ablation of stroma provoke the disruption of corneal nerves and a release of several peptides from tears, epithelium, stroma and nerves. A myriad of cytokines, growth factors, and matrix metalloproteases participate in the process of corneal wound healing. Their balance w...

Steep central island (SCI) formation after photorefractive keratectomy (PRK) and laser in situ keratomileusis (LASIK) represents a major drawback in the visual rehabilitation of patients after refractive laser surgery. Because of the small size of SCIs, current ablation algorithms are unable to properly calculate an ablation pattern for customized retreatment. We present the use of a new ablati...

PURPOSE To report the use of photorefractive keratectomy (PRK) with mitomycin-C (MMC) to treat concomitant myopia and visually significant infiltrates associated with epidemic keratoconjunctivitis (EKC). SETTING Ophthalmic Consultants of Long Island, Nassau University, Long Island, New York, USA. DESIGN Interventional case series. METHODS Consecutive patients with myopia and recalcitrant ...

PURPOSE To evaluate preliminarily the safety and efficacy of customized photorefractive keratectomy (PRK) to correct ametropia and irregular astigmatism after penetrating keratoplasty (PK). METHODS This pilot study included five eyes of five patients with a mean spherical equivalent of -5.1±1.46D (range from -2.75 to -6.50D). In all cases, ametropia and irregular astigmatism was corrected wit...

PURPOSE To assess the effects of topical corticosteroids (fluoromethalone) following photorefractive keratectomy (PRK). METHODS Both eyes of 654 patients had PRK with a minimum of 4 months between treatments. Topical corticosteroids were prescribed for one eye only. Endpoints were assessed by comparing the ratio of intended to actual refractive change in the corticosteroid treated eye with th...

PRK AND ROCK ARE REQUIRED FOR THROMBIN-INDUCED ENDOTHELIAL CELL PERMEABILITY DOWNSTREAM FROM Gα12/13 and Gα11/q Julie Gavard and J Silvio Gutkind From 1 Oral and Pharyngeal Cancer Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland 20892 Running head: RhoA bifurcation on ROCK and PRK *Address correspondance to: Julie Gavard, Ph.D., C...

purpose: to compare tear secretion values following lasik (laser in situ keratomileusis) and photorefractive keratectomy (prk). methods: patients referred to aban eye clinic (isfahan, iran) for refractive surgery were randomly assigned to lasik or prk. exclusion criteria were contraindications for refractive surgery, usage of topical ocular drugs, dry eye and reoperation. schirmer test was perf...