BACKGROUND This was an indirect comparison of the effectiveness of intravitreal aflibercept (IVT-AFL) 2 mg every 8 weeks after 5 initial monthly doses (or if different periods, after an initial monthly dosing period) (2q8) and other diabetic macular edema (DME) therapies at doses licensed outside the USA. METHODS A comprehensive search was undertaken to source relevant studies. Feasibility ne...

BACKGROUND Few data are available on the usefulness of short term treatment with low-medium dose of inhaled corticosteroids (ICS) in pre-school children with wheezing exacerbations. METHODS To compare the efficacy of one week treatment with 400 μg b.i.d. nebulized beclomethasone dipropionate (BDP), plus nebulized 2500 μg prn salbutamol (BDP group), versus nebulized b.i.d. placebo, plus nebuli...

Efficient management of rather limited resources, including radio spectrum and mobile-terminal battery power, has been the fundamental design challenge of wireless networks and one of the most widespread research problems over the years. MAC (Medium Access Control) for packet access and CAC (Call Admission Control) for connection-oriented service domains are commonly used as effective tools to ...

OBJECTIVE To determine the relationship between nurse workload and multiresistant bacteria colonization or infection (MRB+) in a neurology intensive care unit (ICU). METHODS We studied the relationship between nurse workload and MRB+ development in patients who were hospitalized in Dicle University Neurology Department ICU, Turkey during a 6-month period from November 15, 2003 to April 15, 20...

PURPOSE The purpose of this study was to monitor anti-vascular endothelial growth factor (anti-VEGF) treatment regimens for wet age-related macular degeneration (wAMD) in clinical practice and to determine how they impact the physician, patient, and caregiver treatment experience. MATERIALS AND METHODS This was a qualitative analysis based on semistructured interviews with 20 ophthalmologists...

PURPOSE To compare visual and anatomical outcomes of intravitreal injections of bevacizumab and dexamethasone implant (Ozurdex) treatment for macular edema associated with branch retinal vein occlusion (BRVO). METHODS We retrospectively reviewed patients who underwent intravitreal bevacizumab administered monthly on a pro re nata (PRN) basis (26 eyes, IVB group) or an initial 700-μg dexametha...

THE PRN NOTEBOOKTM • VOLUME 7, NUMBER 1 • MARCH 2002 • WWW.PRN.ORG ith so much emphasis being placed on protease inhibitors (PIs) and non-nucleoside reverse transcriptase inhibitors (NNRTIs) in recent years, it’s no wonder that key research involving the “old reliables”—the nucleoside reverse transcriptase inhibitors (NRTIs)—is often overlooked while thumbing through the pages of conference abs...

We previously demonstrated that during nasal air-jet stimulation, both the activities of intrinsic laryngeal adductor and abductor muscles persistently increase, whereas the respiratory cycle prolongs and the activity of diaphragm decreases [Am. J. Rhinol. 9 (1995) 203-208; Neurosci. Res. 31 (1998) 137-146]. The purpose of this study was to clarify the neuronal circuit underlying the augmentati...

ObjectiveTo investigate administration of pro re nata (PRN) medications and nurse-initiated (NIMs) in Australian aged care services over a 12-month period.DesignTwelve-month longitudinal audit medication administrations.Setting participantsThree hundred ninety-two residents 10 regional Victoria, Australia.MethodsRecords PRN NIM were extracted from electronic hard copy charts. Descriptive statis...