نتایج جستجو برای: proadrenomedullin n

تعداد نتایج: 976596  

Journal: :Circulation 2002
Tatsuo Shimosawa Yugo Shibagaki Kotaro Ishibashi Kazuo Kitamura Kenji Kangawa Shigeaki Kato Katsuyuki Ando Toshiro Fujita

BACKGROUND Adrenomedullin (AM), a potent vasodilator peptide, is produced by posttranslational splicing of pro-adrenomedullin together with proadrenomedullin N-terminal 20 peptide (PAMP), another hypotensive peptide. Although both AM and PAMP have the potential not only to decrease blood pressure but also to protect organs from damage, there is no direct evidence for their individual physiologi...

Journal: :Circulation 1998
I Szokodi P Kinnunen P Tavi M Weckström M Tóth H Ruskoaho

BACKGROUND Adrenomedullin (ADM), a new vasorelaxing and natriuretic peptide, may function as an endogenous regulator of cardiac function, because ADM and its binding sites have been found in the heart. We characterize herein the cardiac effects of ADM as well as the underlying signaling pathways in vitro. METHODS AND RESULTS In isolated perfused, paced rat heart preparation, infusion of ADM a...

Journal: :Journal of internal medicine 2011
R Latini S Masson S Pirelli S Barlera G Pulitano E Carbonieri M Gulizia T Vago C Favero D Zdunek J Struck L Staszewsky A P Maggioni M G Franzosi M Disertori

OBJECTIVE we evaluated the prognostic role of circulating cardiovascular biomarkers in patients with a history of recent atrial fibrillation (AF). BACKGROUND predicting long-term maintenance of sinus rhythm in patients with AF is difficult. METHODS plasma concentrations of three specific cardiac markers [high-sensitivity troponin T (hsTnT), N-terminal probrain natriuretic peptide (NT-proBNP...

 Let $R$ be a ring‎, ‎and let $n‎, ‎d$ be non-negative integers‎. ‎A right $R$-module $M$ is called $(n‎, ‎d)$-projective if $Ext^{d+1}_R(M‎, ‎A)=0$ for every $n$-copresented right $R$-module $A$‎. ‎$R$ is called right $n$-cocoherent if every $n$-copresented right $R$-module is $(n+1)$-coprese-nted‎, ‎it is called a right co-$(n,d)$-ring if every right $R$-module is $(n‎, ‎d)$-projective‎. ‎$R$...

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