نتایج جستجو برای: proapoptotic

تعداد نتایج: 5755  

Journal: :The Journal of Internal Korean Medicine 2022

Objectives: Acanthopanax senticosus is a tree used in traditional medicine for various diseases. In this study, we investigated the anti-cancer effects of water extract senticocus fruit (ASF) on 2 human breast cancer cell lines (MCF-7 and MDA-MB-231).Methods: The MTT assay was to assess proliferation. expression apoptosis-related genes assessed by quantitative real-time PCR.Results: ASF treatme...

2012
Garnet J. Lau Nicolas Godin Hasna Maachi Chao-Sheng Lo Shyh-Jong Wu Jian-Xin Zhu Marie-Luise Brezniceanu Isabelle Chénier Joelle Fragasso-Marquis Jean-Baptiste Lattouf Jean Ethier Janos G. Filep Julie R. Ingelfinger Viji Nair Matthias Kretzler Clemens D. Cohen Shao-Ling Zhang John S.D. Chan

This study investigated the mechanisms underlying tubular apoptosis in diabetes by identifying proapoptotic genes that are differentially upregulated by reactive oxygen species in renal proximal tubular cells (RPTCs) in models of diabetes. Total RNAs isolated from renal proximal tubules (RPTs) of 20-week-old heterozygous db/m+, db/db, and db/db catalase (CAT)-transgenic (Tg) mice were used for ...

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