In this current study, antiproliferative effect of Hec1/Nek2 Mitotic Pathway inhibitor INH1 was investigated in adenocarcinomic human alveolar basal epithelial cells A549 and cervix carcinoma HeLa cell lines vitro. To end index values by xCELLigence Real‐Time Cell Analysis DP instrument, mitotic index, BrdU proliferation assay apoptotic analysis were used. The results the study showed that had ...

the role of antioxidants in prevention and treatment of cancers have been reported by several studies. in our investigation we studied the effects of ascorbic acid, ?-tocopherol, and sodium selenite on proliferation of two breast cancer cell lines: t47d (estrogen-receptor positive) and mda-mb-231 (estrogen-receptor negative). we also used 17-?-estradiol as positive control for proliferation of ...

objectives: this study investigated the possible synergistic effect of simultaneous treatment of bone morphogenic protein (bmp)-4 as a chemical stimulator and static magnetic field (smf) as a physical stimulator on viability percent and proliferation rate in rat bone marrow stem cells. methods: passage 5 cells were trypsinized, and a cell suspension prepared after which the cells were counted ...

in addition to its antioxidant effect, vitamin e or α–tocopherol is suggested to enhance remyelination in the animal model of non-inflammatory demyelination. in this study, the possible proliferative effect of vitamin e on human- induced pluripotent stem cell-derived neural progenitors (hips-nps) and the underlying mechanisms were investigated in vitro. nps were induced from ips cells via 3 ste...

olea europaea l. commonly known as olive has been traditionally used for the prevention and treatment of many diseases since ancient times. olive has been reported to possess a broad spectrum of pharmacological properties. in the present study we investigated the activity of aqueous extract of olea europaea l. fruit at various concentrations on a2780, a172 and hfff2 cell lines proliferation by ...

Objective: Helicobacter pylori has a well-established role in the development of gastric cancer. In vitro studies reveal increased proliferation of the gastric mucosa in the presence of H. pylori infection. It has been also shown that production of some cytokines, such as interleukin-1 beta (IL-1b) is in...

The effect of dietary starch, fat, and cellulose on colonic proliferation was studied in female C57Bl/6J mice after 4 weeks of feeding with diets containing various levels of starch (3, 36, and 57-65%), various levels of fat (corn oil, 5 and 29%) and various levels of cellulose (2 and 10%). Cell proliferation was measured by colchicine arrest and [3H]thymidine incorporation. The following param...

in this work, we report the effect of biopolymers (starch and gelatin) on in vitro biocompatibility property of nano hydroxyapatite (nhap) composites. cell culture and mtt assays were performed for in vitro biocompatibility. they show that nhap can affect the proliferation of cells and the nhap-starch and nhap-gelatin biocomposites have no negative effect on the cell morphology, viability and p...

purpose: to evaluate the effect of human amniotic fluid (haf) on the growth of human corneal endothelial cells (hcecs) and to establish an in vitro method for the expansion of hcecs. methods: hcecs were cultured in dmem-f12 supplemented with 20% fetal bovine serum (fbs). confluent monolayer cultures were trypsinized and passaged using 20% fbs- or 10%, 20%, or 30% haf-containing media. cell prol...