| This paper presents a region-based coding algorithm for video sequences. The coding approach involves a time-recursive segmentation relying on the pixels ho-mogeneity, a region-based motion estimation, and motion compensated contour and texture coding. This algorithm is mainly devoted to very low bit rate video coding applications. One of the important features of the approach is that no assu...

the aim of this paper is to improve the performance of the conventional goertzel algorithm in determining the protein codingregions in deoxyribonucleic acid (dna) sequences. first, the symbolic dna sequences are converted into numerical signals usingelectron ion interaction potential method. then by combining the modified anti-notch filter and linear predictive coding model,we proposed an effic...

We have determined the DNA sequence of the long repeat region (RL) in the genome of herpes simplex virus type 1 (HSV-1) strain 17, as 9215 bp of composition 71.6% G + C. In addition, the sequences of parts of the long unique region (UL) adjacent to the terminal (TRL) and internal (IRL) copies of RL were determined (2611 and 3836 bp, respectively). Gene organization in these regions of UL was de...

We recently showed loss of pRb in a proportion of pituitary tumors that was not associated with loss of heterozygosity of an RB1 intragenic marker. To further define the mechanism responsible for loss of retinoblastoma protein (pRb) expression, we have investigated the methylation status of the CpG island contained within the promoter region of the RB1 gene, together with sequence analysis of t...

Single nucleotide polymorphisms (SNPs) represent the most common type of variation in the human genome. The SNPs located in protein-coding and non-coding RNA genes are classified as neutral and functional. The neutral have no effect, while the functional affect different biological processes and continually confer risk for multifactorial diseases. Functional SNPs found in the promoters of prote...

The prediction of protein coding regions in DNA sequences is an important problem in computational biology. It is observed that nucleotides in the protein coding regions or exons of a DNA sequence show period-3 property. Hence identification of the period-3 regions helps in predicting the gene locations within the billions long DNA sequence of eukaryotic cells. The period-3 property exhibited i...

BACKGROUND As Lens epithelium-derived growth factor (LEDGF/p75) is an important co-factor involved in HIV-1 integration, the LEDGF/p75-IN interaction is a promising target for the new class of allosteric HIV integrase inhibitors (LEDGINs). Few data are available on the genetic variability of LEDGF/p75 and the influence on HIV disease in vivo. This study evaluated the relation between LEDGF/p75 ...

In this paper, the secrecy problem in the state dependent causal cognitive interference channel is studied. The channel state is non-causally known at the cognitive encoder. The message of the cognitive encoder must be kept secret from the primary receiver. We use a coding scheme which is a combination of compress-and-forward strategy with Marton coding, Gel’fand-Pinsker coding and Wyner’s wire...

The DNA sequence of the Escherichia coli metK gene has been determined. Protein sequence data for purified S-adenosylmethionine synthetase have also been obtained and confirm that metK is the structural gene for S-adenosylmethionine synthetase in E. coli. The sequence of the amino-terminal 35 residues of purified S-adenosylmethionine synthetase localizes the beginning of the coding region of th...

To clarify the binding properties of hepatitis C virus (HCV) core protein and its viral RNA for the encapsidation, morphogenesis, and replication of HCV, the specific interaction of HCV core protein with its genomic RNA synthesized in vitro was examined in an in vivo system. The positive-sense RNA from the 5' end to nucleotide (nt) 2327, which covers the 5' untranslated region (5'UTR) and a par...