# 1999 International Union of Crystallography Printed in Great Britain ± all rights reserved The Protein Data Bank (PDB) has long made available the experimental data which were used to determine the three-dimensional structures in the database. In recent years more and more depositors and users of the PDB have come to appreciate the importance of reliable access to such fundamental data. The d...

In mammals, histone H3.3 is a critical regulator of transcription state change and heritability at both euchromatin and heterochromatin. The H3.3-specific chaperone, DAXX, together with the chromatin-remodeling factor, ATRX, regulates H3.3 deposition and transcriptional silencing at repetitive DNA, including pericentromeres and telomeres. However, the events that precede H3.3 nucleosome incorpo...

Paracoccidioidomycosis is a chronic granulomatous disease caused by the fungus Paracoccidioides brasiliensis. Although eosinophils have long been associated with the immune defense against helminths, the role of eosinophils in the immune response to fungal diseases is not as well studied. The eosinophil granule major basic protein is toxic to helminths and mammalian cells in vitro, and its rele...

Background The specific pathological findings in Alzheimer’s disease (AD) brain are senile plaques composed of amyloid-β protein (Aβ) and neurofibrillary tangles (NFTs) highly phosphorylated tau protein. It has been suggested that autophagy may play an important role the degradation proteins. In this study, we investigated whether is involved oligomeric by immunohistochemistry using autopsied A...

In this work, a slippery liquid-infused silver-polytetrafluoroethylene (AgFP) coating was fabricated via spontaneous polycondensation of 1H,1H,2H,2H-perfluorooctyltriethoxysilane (PFOTES) onto an electroless AgF sublayer. The AgFP demonstrated great stability and superior repellence against liquids with wide range surface tensions. anti-biofouling properties were investigated by adsorption Esch...

Molecular layer deposition (MLD) was used to coat micron-sized protein particles in a fluidized bed reactor. Our results show that the dissolution rate of particles coated via MLD rapidly decreases with the increase in number of coating cycles, while the uncoated particles dissolve instantaneously.

Recent developments in the electrokinetic determination of particle, protein and polyelectrolyte monolayers at solid/electrolyte interfaces, are reviewed. Illustrative theoretical results characterizing particle transport to interfaces are presented, especially analytical formulae for the limiting flux under various deposition regimes and expressions for diffusion coefficients of various partic...

Abstract High surface area carbon coatings are produced by plasma‐enhanced chemical vapour deposition using a high‐voltage dielectric barrier discharge under conditions where aggregates formed in the plasma and growing coating is subjected to immersion ion implantation. We extend Smoluchowski aggregation theory include continuous production of monomers explain observed microstructure as functio...