نتایج جستجو برای: protein kinase

تعداد نتایج: 1318333  

The objective of this study is to investigate the anti-tumor effect of Ginkgo biloba exocarp extracts (GBEE) on B16 melanoma bearing mice and its related molecular mechanisms. The B16-F10 melanoma solid tumor model was established in C57BL/6J mice. The tumor-bearing mice were treated with GBEE (50, 100, 200 mg/kg), taking cis-Dichlorodiamineplatinum (Ⅱ) (DDP, 3 mg/kg) as pos...

Journal: :Oncology Letters 2023

The most common tumor affecting the head and neck is squamous cell carcinoma (HNSCC). characteristics of HNSCC include a rapid onset, lack early diagnosis, drug resistance, relapse systemic adverse effects, leading to inadequate prevention, diagnosis treatment. Notably, previous research suggests that there an association between S100 proteins HNSCC. S100A8, S100A9 S100A14 interfere with prolif...

Journal: :International journal of chemistry research 2022

Objective: The present study discusses the molecular docking of Hentriacontane for its Anti-tubercular and Anti-cancer activity. Methods: Two protein targets were selected their structures taken from RCSB Protein Data Bank in PDB format. Preparation proteins was done using Discovery Studio 2021 Client. structure drawn ChemDraw 20.0 saved Mol Molecular performed PyRx software. 3D 2D interactions...

Journal: :Atlas of Genetics and Cytogenetics in Oncology and Haematology 2012

Talaei, Alireza, Aghighi, Fatemeh , Salami, Mahmoud ,

Introduction: The prenatal stress is a key factor which affects the growth and function of the brain. Several studies have shown that prenatal stress induces deficits in learning and memory of the offspring. The prenatal stress alters the activity of neurotransmitters, such as noradrenaline, dopamine and serotonin, via over-activation of the hypothalamic–pituitary–adrenal axis. In addition, the...

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