نتایج جستجو برای: proteolytic

تعداد نتایج: 22072  

2016
Ioannis Sakaridis

The relation between age gelation and proteolytic activity was investigated in this study, as proteolysis is considered to be one of the principal factors that cause gelation. Two different methods for measuring the proteolytic activity of milk samples were applied; the measurement of absorbance at 280 nm and the trinitrobenzene sulfonic acid (TNBS) method. The milk samples used were raw and UH...

Journal: :Report. Army Medical Research Laboratory 1965
J H BROWN

EFFECT OF El7MTI FUNC.T]DN'AL GROUP INBI3ITORS ON PRGIE)0LTELYT ZYBMKU OF TA-3 S ATMO' WIEi1N C C43T To determine the effects of several functionaL group,-specific inhib=Qrsof enzymes and: of metal ioneon. the activityof the proteolytic enzymes of Crotalusatrmx venom.. To attempt M discern the typeand: number of proteolytic enzymes presenti m crude venom and: to obtain & detoxified,, yet immu.n...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2013
Daniel Fleck Frauke van Bebber Alessio Colombo Chiara Galante Benjamin M Schwenk Linnea Rabe Heike Hampel Bozidar Novak Elisabeth Kremmer Sabina Tahirovic Dieter Edbauer Stefan F Lichtenthaler Bettina Schmid Michael Willem Christian Haass

Proteolytic shedding of cell surface proteins generates paracrine signals involved in numerous signaling pathways. Neuregulin 1 (NRG1) type III is involved in myelination of the peripheral nervous system, for which it requires proteolytic activation by proteases of the ADAM family and BACE1. These proteases are major therapeutic targets for the prevention of Alzheimer's disease because they are...

2014
Oliver Holmes Swetha Paturi Dennis J. Selkoe Michael S. Wolfe

The 19-transmembrane γ-secretase complex generates the amyloid β-peptide of Alzheimer's disease by intramembrane proteolysis of the β-amyloid precursor protein. This complex is comprised of presenilin, Aph1, nicastrin, and Pen-2. The exact function and mechanism of the highly conserved Pen-2 subunit remain poorly understood. Using systematic mutagenesis, we confirm and extend our understanding ...

Journal: :Biochemistry 2022

Proteolytic enzymes are well known for catalyzing hydrolytic reactions. These fall under the group of large and complex, also as proteases. mainly derived from microbial origin favored because they have a short generation time, ease genetic manipulation microorganisms, availability diverse species in nature. Macro fungi significant played an excellent role degrading lignocellulosic compounds, s...

Journal: :Sains Malaysiana 2021

Hypertension is a significant public health problem worldwide, leading risk factor for cardiovascular disease and cause of premature death. Angiotensin-I-converting enzyme (ACE) activity one the causes hypertension. Lamtoro Gung has potential as an Enzyme Inhibitory (ACE-I) due to presence peptide that able inhibit its prevent The germination process was carried out hydrolyse storage proteins p...

2007
Yoshinobu Igarashi Alexey M. Eroshkin Svetlana Gramatikova Kosi Gramatikoff Ying Zhang Jeffrey W. Smith Andrei Osterman Adam Godzik

Beyond the well-known role of proteolytic machinery in protein degradation and turnover, many specialized proteases play a key role in various regulatory processes. Thousands of highly specific proteolytic events are associated with normal and pathological conditions, including bacterial and viral infections. However, the information about individual proteolytic events is dispersed over multipl...

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