abstract background: oligodendrogliomas are sub-types of gliomas with an enriched net of branching capillary. a vast amount of oligodendroglial (approximately 60-90%) demonstrates a loss of 1p and 19q chromosomes, and their response to radio and chemotherapy treatments are considerably more favorable and less aggressive. rho gdp inhibitor is a protein which controls the activity and distributio...

esophagus cancer is the eighth most common cancer worldwide and particularly high in an area extending from the southern border of the caspian sea in iran across central asia to china. since information about this mysterious disease is poor, proteomics may be solving this enigma. altering gene expression in cancer cell is a remarkable indicator can be detected by proteomics techniques and bioin...

Complexome profiling is a novel technique which uses shotgun proteomics to establish protein migration profiles from fractionated blue native electrophoresis gels. Here we present a dataset of blue native electrophoresis migration profiles for 953 proteins by complexome profiling. By analysis of mitochondrial ribosomal complexes we demonstrate its potential to verify putative protein-protein in...

U niversal principles underlying network science and their ever-increasing applications in biomedicine underscore the unprecedented capacity of systems biology–based strategies to synthesize and resolve massive high-throughput generated data sets. Enabling previously unattainable comprehension of biological complexity, systems approaches have accelerated progress in elucidating disease predicti...

Harmine is a beta-carboline alkaloid found in medicinal plant PeganumHarmala, which has served as a folk anticancer medicine. However, clinical applications of harmine were limited by its low pharmacological effects and noticeable neurotoxicity. In this study, we modified harmine to increase the therapeutic efficacy and to decrease the systemic toxicity. Specifically, two tumor targeting harmin...

Millimeter Waves (MMW) will be used in the next-generation of high-speed wireless technologies, especially in future Ultra-Broadband small cells in 5G cellular networks. Therefore, their biocompatibilities must be evaluated prior to their massive deployment. Using a microarray-based approach, we analyzed modifications to the whole genome of a human keratinocyte model that was exposed at 60.4 GH...

ethanol known as ethyl alcohol is being widely used around the world. many serious diseases are related with its consumption.  alcohol posses many divers effects on human body including risk of cirrhosis and/or hepatocellular carcinoma. therefore, analysis of this component is prominent. fibroblast cells were cultured in various dosages of ethanol. the effective dosage was then investigated by ...