Abstract Background and Aims Human kidneys have a role in water homeostasis, acid-base control, reabsorption of compounds, secretion xenobiotics endogenous metabolites, exposing them to substances that could cause harm. This results an alarming number acute kidney injuries (AKI) worldwide, estimated at 13%. Furthermore, one-quarter hospitalised cases are due drug-induced AKI [1]. Current method...

Abstract Objectives This study aimed to evaluate how health-related quality of life (HRQOL) is related repeat protocol biopsy compliance. Materials and methods We conducted a retrospective analysis using data from prospective cohort in the Prostate Cancer Research International: Active Surveillance (PRIAS)-JAPAN between January 2010 August 2019. used Short Form 8 Health Survey (SF-8), as patien...

abstract   background: wound infection is a frequent and severe complication in burn patients accounting for a high number of mortalities. there are some reports comparing swab and biopsy cultures of wounds of various etiologies or chronic wounds.   objectives: the aim of the study was to evaluate burn wound infection by different bacteriologic methods of surface swab and tissue biopsy culture ...

I propose that a patient with a clinical diagnosis of Barrett’s oesophagus (BO) must have regularly endoscopic surveillance and protocol biopsy. BO is defined by endoscopically visible oesophageal columnar epithelium with intestinal metaplasia. The purpose of screening is detection of dysplastic change and early cancer, to allow early intervention and prevention of the suffering of symptomatic ...

Background This prospective study was designed to examine the role of fibrosis staging on selection and success of treatment options for autoimmune hepatitis (AIH). Materials and Methods The project was conducted on 110 selected AIH patients who, based on the results of liver biopsy, had been assigned into one of the three groups (mild, stages 1 and 2, moderate, stages 3 and 4, and severe, stag...

BACKGROUND AND STUDY AIMS The current gold standard in Barrett's esophagus monitoring consists of four-quadrant biopsies every 1-2 cm in accordance with the Seattle protocol. Adding brush cytology processed by digital image cytometry (DICM) may further increase the detection of patients with Barrett's esophagus who are at risk of neoplasia. The aim of the present study was to assess the additio...

OBJECTIVES To quantify the degree of pain experienced by patients who undergo ultrasound-guided transrectal prostate biopsy in standard clinical practice and assess the clinical factors associated with increased pain. MATERIAL AND METHODS Analysis of a multicenter series of patients with prostate biopsy according to standard clinical practice. The biopsy was performed transrectally with a pro...

Chronic allograft nephropathy (CAN) represents a frequent and irreversible cause of long-term renal graft loss. TGF-beta1 is a key profibrogenic cytokine associated with CAN pathogenesis. Because of clinical diagnostic inaccuracy, protocol biopsy has been suggested to be a beneficial method for early CAN detection. Protocol core biopsy was carried out in 67 consecutive cyclosporine-based immuno...

background : lung cancer is still the leading cause of cancer- related deaths and most of themâ  are normally diagnosed in late stages, so there is an urgent need to establish reliable tools for the identification at early stages of the disease. in this study, we use an eleven gene signature test to examine lung biopsy specimens for diagnostic, prognostic & therapeutic purposes. methods : bronc...

BACKGROUND/AIM Diagnostic procedures during the detection of cervical intraepithelial lesions (CIN) are a combination of cytology, colposcopy, punch biopsy and endocervical curretage. An optimal therapeutic approach according to the distribution, size and grade of cervical lesions is the result of this diagnostic protocol. This study was carried out to assess reliability of the punch biopsy and...