A surgical technique was designed to improve safety after pterygium excision with intraoperative application of mitomycin-C (MMC). A limbic incision was performed in 40 eyes. The body of the pterygium was dissected from the episclera to allow its excision. Care was taken to avoid excessive delamination and cauterization of tissues. A 0.02% MMC solution was then applied. Only at the end of the s...

BACKGROUND We report a rare case of carcinoma in situ (CIS) in conjunction with a primary pterygium that exhibited characteristic angiographic and histopathological findings. CASE A 78-year-old man presented with a pterygium and a whitish tumor adjacent to the pterygium in his right eye. Indocyanine green angiography displayed that feeder vessels within the primary pterygium spread to the whi...

My guests in this corneal dissection column, John A. Hovanesian, MD, FACS, and Andrew Behesnilian, BS, describe their surgical technique of using amniotic membrane transplantation as a “biologic implant” beneath the normal conjunctiva surrounding the region where the pterygium is excised and replaced with a conjunctival autograft. They said the recurrence rate of 5% after pterygium surgery comb...

The popliteal pterygium syndrome is a highly characteristic congenital malformation syndrome affecting the face, limbs, and genitalia. Gorlin et all 2 coined the term 'popliteal pterygium syndrome' on the basis of the most unusual anomaly, the popliteal web. In some publications the names of Fevre and Languepin3 are used as an eponym. A more descriptive term suggested for the condition, on the ...

purpose: to determine the efficacy and safety of subconjuctival injection of mitomycin c versus daunorubicin for treatment of pterygium. methods: this randomized double blind placebo-controlled clinical trial included 54 eyes of 36 patients with pterygium who were referred to al-zahra hospital, zahedan-iran in 2004. eyes were randomly assigned to three groups including mitomycin c, daunorubicin...

Objective: To evaluate the inhibition of fibroblast proliferation in vitro conjunctiva obtained by excision pterygium from patients using mitomycin (MMC) and cyclophosphamide (CF). Methods: Pterygiums were removed 7 subjected to cell culture. After cultivation, 3 fragments equal dimensions these tissues collected adjacent areas each patient pterygium. They randomly selected such a way that one ...

results of 50 patients, 20 were men and 30 women with mean age of 61.1 ± 16.9 years ranged between 22 and 85 years. all samples of pterygia had positive results for adenoviruses dna with polymerase chain reaction, but none of the negative control groups displayed adenoviruses. the pterygium group and the control groups were β-globin positive. direct sequencing of pcr products confirmed adenovir...

The purpose of this study was to compare the inhibitory effect of bevacizumab on human Tenon's fibroblasts (HTFs) cultured from primary and recurrent pterygium. Cultured HTFs were exposed to 2.0, 5.0, 7.5, and 15.0 mg/mL concentration of bevacizumab for 24 hours. The 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl tetrazolium bromide and lactate dehydrogenase leakage assays were then performed to ass...

PURPOSE To evaluate the efficacy and safety of pterygium excision using a large conjunctival autograft for the treatment of recurrent pterygium. METHODS The medical records of 120 patients (126 eyes) with recurrent pterygium were reviewed. For each affected eye, pterygium excision with a large conjunctival autograft was performed. The graft was harvested from the superior bulbar area and meas...

PURPOSE Little is known about DNA damage in human pterygium, and no data about DNA damage involvement as a potential angiogenic factor are available. We studied, with immunohistochemistry, the presence and localization of thymine dimers in the epithelial and stromal components of the human primary pterygium and its recurrences with a special emphasis on the vascular network and its interactions...