OBJECTIVES Idiopathic central precocious puberty and its postponement with a (gonadotropin-releasing hormone) GnRH agonist are complex conditions, the final effects of which on bone mass are difficult to define. We evaluated bone mass, body composition, and bone remodeling in two groups of girls with idiopathic central precocious puberty, namely one group that was assessed at diagnosis and a se...

During the transitioning through puberty, adolescents present with varied gynaecological issues, among which puberty menorrhagia is a significant complaint. The most common underlying cause of puberty menorrhagia is anovulation, other causes being endocrine dysfunction, PCOS and bleeding disorders. Congenital prothrombin deficiency is an extremely rare inherited coagulopathy, affecting one in t...

Age of puberty onset is considered to be of general public health relevance. A downward secular trend in age of puberty onset has now been repeatedly reported in both developed (1) and developing countries (2). Early puberty onset has been suggested to be a risk factor for a series of diseases in later life, including hormone-related cancer, type 2 diabetes mellitus, metabolic syndrome, cardiov...

BACKGROUND The mechanism that initiates the onset of puberty is largely unknown but the age of onset is mainly under genetic control and influenced by environmental factors including nutrition. The coexistence in the same family of central precocious puberty and advanced puberty, both representing early puberty, suggests that they may represent a clinical spectrum of the same trait due to early...

objective: to compare sexual and behavioral puberty problems between intellectually disabled (id) and normal boys in yazd, iran. methods: in the present study, 65 intellectually disabled and 65 normal boys were included. the child behavior check list (cbcl) was used to investigate behavioral problems. in order to study sexual problems, a questionnaire that was designed by the researchers was ap...

Adolescents need accurate information about puberty, because adolescents who fail to go through the puberty phase may experience psychological disorders that have an impact on next of life. This service activity is carried out disseminate by utilizing Instagram media. The specific purpose this make understand definition when occurs, changes generally occur during and correct attitude in dealing...

a 29- year old female with bone pain and history of precocious puberty was referred for bone scintigraphy. on physical examination café au lait macular spots were noted on her neck, buttocks and left leg. bone scan showed multiple areas of intense increased activity which was in favour of polyostotic fibrous dysplasia. considering the presence of polyostotic fibrous dysplasia, precocious pubert...

BACKGROUND Puberty moderates genetic influences on disordered eating attitudes and behaviors, with little genetic influence before puberty but large (50%) genetic effects during and after puberty. To date, however, nothing is known about the mechanisms that underlie these effects. Estradiol is a particularly promising candidate, as estrogens become elevated at puberty and regulate gene transcri...