In India, pulmonary tuberculosis accounts for 85% of cases and extrapulmonary tuberculosis accounts for 15% of cases with bone and joint involvement is seen in 1 to 3% of cases. Primary tuberculous osteomyelitis of the sternum is a rare form of extrapulmonary tuberculosis. A 51-year-old male presented with 10 years history of swelling over the anterior chest wall and pain for past 6 months. Fin...

BACKGROUND & OBJECTIVES As isolation of Mycobacterium tuberculosis in culture requires a long time, there is a need for simple rapid method for direct detection of M. tuberculosis from clinical specimens. Amplified nucleic acid hybridization assays such as polymerase chain reaction (PCR) have shown promising results. In the present study, the sensitivity of PCR assay was assessed over smear mic...

conclusions the detection of mycobacterium tuberculosis is always an important differential diagnosis for skin and soft tissue involvement in endemic areas. the cold abscess is an uncommon form of cutaneous tuberculosis that can be single or multiple and with or without fistula. case presentation the case was a 42-year-old female, a known case of rheumatoid arthritis that was receiving predniso...

The potentially pathogenic Non-Tuberculosis Mycobacteria (NTM) are emerging nowadays which result in pulmonary and non-pulmonary infections in human. This group of bacteria consists of at least 200 different species. While the pulmonary disease is the most common form of NTM infections, NTM can cause diffused infections as well as extrapulmonary infections in every organ, such as bone marrow, s...

Mycobacterium tuberculosis, the causative agent of tuberculosis was discovered by Robert Koch in 1882. It has been observed that 30% of the world population harbours Mycobacterium tuberculosis. Spread of Human immunodeficiency virus (HIV) infection, malignancies, globalization and malnutrition are some of the major contributing factors for increase in the global burden of tuberculosis (pulmonar...

background according to several studies, diabetes mellitus has been recognized as one of the main risk factors for pulmonary tuberculosis (ptb). objectives the main purpose of this study was to determine the frequency of smear-positive pulmonary tuberculosis (tb) in patients with diabetes. materials and methods this cross-sectional study was conducted from april 2010 to december 2011 in ali asg...

the aim of this study was to determine the association of n-acetyltransferase-2 polymorphisms and anti-tuberculosis drug-induced hepatotoxicity in iranian pulmonary tuberculosis patients. acetylating phenotypes was studied in 50 iranian pulmonary tuberculosis patients using metabolic ratio of plasma acetyl-isoniazid to isoniazid. the association between hepatotoxicity and the n-acetyltransferas...

 Abstract Thymic carcinoid is an uncommon neoplasm that can present with Cushing syndrome. We report a 39-year old woman with symptoms of Cushing syndrome secondary to thymic carcinoid and synchronous with tuberculous lymphadenitis and pulmonary tuberculosis. 

BACKGROUND Clinical suspects of pulmonary tuberculosis in which the sputum smears are negative for acid fast bacilli represent a diagnostic challenge in resource constrained settings. Our objective was to validate an existing clinical-radiographic score that assessed the probability of smear-negative pulmonary tuberculosis (SNPT) in high incidence settings in Peru. METHODOLOGY/PRINCIPAL FINDI...