Hereditary hemorrhagic telangiectasia (HHT; Osler-Weber-Rendu syndrome) is an uncommon disease characterized by abnormal telangiectasias and arteriovenous malformations that cause recurrent bleeding. Here, we present the case of a patient with HHT, who had a history of pulmonary and hepatic arteriovenous malformations and endocarditis of a prosthetic aortic valve that was caused by methicillin-...

A total of 14 cases of infective endocarditis (IE) in children aged 6 months to 10 years were seen from December 1987 to December 1992 at the pediatric unit of Ayatollah Taleghani Medical Center. The majority of patients (12 of 14) were between 5 and 10 years of age. Acyanotic congenital heart disease was known to preexist in 78.6% and rheumatic valvular heart disease in 21.4% of cases. Or...

A 46-year-old man, known to have an undiagnosed asymptomatic congenital heart defect, had a high temperature in November 1979. He was treated with antibiotics which were at first effective but pyrexia reappeared two weeks later. Cephalosporin was given intravenously for 10 days, but the patient became very weak, and haemorrhagic purpura appeared on the legs; evening pyrexia persisted. Finally, ...

Background: Infectious endocarditis is caused by bacterial or fungal infections of the endocardial surface heart, with high morbidity and mortality. Information on infective low in a developing country, Iran, situation similar, so far no accurate research epidemiology has been carried out. The aim study to epidemiological evaluation Infective endocarditis.Methods: This cross-sectional was done ...

Congenital heart disease (CHD) is one of the risk factors for developing infective endocarditis (IE). Right-sided IE occurs in 5%–10% cases, and pulmonary valve (PV) involved less than 2% such patients. Literature data are few, optimal treatment methods, indications surgery, types operative techniques still under debate. We present an adult patient with a rare combination ventricular septal def...

IN THE PAST THREE DECADES a striking change has occurred in the microbiological spectra, clinical features and natural history of infective endocarditis. Undoubtedly, the development of a host of potent antimicrobial agents and their widespread availability and, at times, indiscriminate use, have played a key role. Other important factors include the use of prosthetic heart valves, the increasi...

IN THE PAST THREE DECADES a striking change has occurred in the microbiological spectra, clinical features and natural history of infective endocarditis. Undoubtedly, the development of a host of potent antimicrobial agents and their widespread availability and, at times, indiscriminate use, have played a key role. Other important factors include the use of prosthetic heart valves, the increasi...

Infective endocarditis is an uncommon heart disease with a variable incidence, mostly related to the ever-increasing development of cardiac surgery and the longer survival of patients with congenital heart disease (CHD). Thirty-seven episodes of infective endocarditis (IE) were evaluated in 36 children (under 15 years of age) admitted to hospitals affiliated to Shiraz University of Medical ...

A 52 years old patient is hospitalized in June 2007 in the Cardiology Clinic of Cardiovascular Diseases Medical Institute in Iasi with suspected subacute infectious endocarditis. Echocardiography shows mobile vegetation on the pulmonary valve. Acremonium spp is isolated from blood cultures after 2 weeks of incubation. The patient was treated with fluconazole, but died after 3 months due to rena...