Amlodepine poisioning is rare. Amlodepine toxicity presents as hypotension, pulmonary oedema both cardiogenic and non-cardiogenic. Standard approaches to the management of calcium channel blocker overdoses, including fluid resuscitation, gut decontamination, administration of calcium, as well as supportive care, are often ineffective. pWe report a case of amlodepine poisioning with acute respir...

OBJECTIVE People with epilepsy (PWE) develop complications and comorbidities often requiring admission to hospital, which adds to the burden on the health system, particularly in low-income countries. We determined the incidence, disability-adjusted life years (DALYs), risk factors, and causes of admissions in PWE. We also examined the predictors of prolonged hospital stay and death using data ...

PURPOSE Aggression in people with epilepsy (PWE) is not well understood. We investigated interictal aggression in PWE and clarified predictors and the interrelationships among them. METHOD This was a case-control study. Eligible subjects who consecutively visited the epilepsy clinic completed several questionnaires including the Aggression Questionnaire (AQ), the Revised Stigma Scale (RSS), t...

BACKGROUND The objective of this study is to conduct a systematic review of studies reporting the frequency of neurocysticercosis (NCC) worldwide. METHODS/PRINCIPAL FINDINGS PubMed, Commonwealth Agricultural Bureau (CAB) abstracts and 23 international databases were systematically searched for articles published from January 1, 1990 to June 1, 2008. Articles were evaluated for inclusion by at...

To facilitate therapeutic monitoring of antiepileptic drugs (AEDs) by healthcare professionals for patients with epilepsy (PWE), we applied a GC-MS assay to measure three AEDs: carbamazepine (CBZ), phenytoin (PHT) and valproic acid (VPA) levels concurrently in one dried blood spot (DBS), and validated the DBS-measured levels to their plasma levels. 169 PWE on either mono- or polytherapy of CBZ,...

About 30% of people with epilepsy (PWE) are drug-resistant. Those focal seizures may be suitable for surgery. not amenable to resective surgery can considered vagus nerve stimulation (VNS). However, after operative procedures, around 50% patients continue experience seizures. A multi-center retrospective study assessing perampanel effectiveness and tolerability PWE who have undergone surgical r...