P pili are protein filaments expressed by uropathogenic Escherichia coli that mediate binding to glycolipids on epithelial cell surfaces, which is a prerequisite for bacterial infection. When a bacterium, attached to a cell surface, is exposed to external forces, the pili, which are composed of approximately 10(3) PapA protein subunits arranged in a helical conformation, can elongate by unfoldi...

Pyoderma gangrenosum is a rare but significant cause of ulcerations. It is a diagnosis of exclusion. Herein, we suggest diagnostic criteria and some historical perspectives on the diagnosis of pyoderma gangrenosum.

Moore, G. R., Huang, Z.-X., Eley, C. G. S., Barker, H. A., Williams, G., Robinson, M. N. & Williams, R. J. P. (1982) Furuduy Discuss. Chem. SOC. 74, 31 1-329 Papa, S. (1976) Biochim. Biophys. Acta 456, 39-84 Slater, E. C. (1983) Trends Biochem. Sci. 8, 239-245 Wikstrom, M. K. F. & Krebs, K. (1979) Biochim. Biophys. Acta 549, 177-222 Williams, R. J. P. (1961) J. Theor. Biol. 1, 1-17 Williams, R....

Previous research has examined the consequences of either expressing or suppressing emotion using between-subjects designs. However, emotion theorists have argued that adaptation depends not so much on one regulatory process but rather on the ability to flexibly regulate emotion in accord with situational demands. To test this idea, Bonanno, Papa, Lalande, Westphal, and Coifman (2004) developed...

Obstet Gynecol 2002;187:1125–30. 3. Mannello F, Luchetti F, Canonico B, Papa S. Effect of anticoagulants and cell separation media as preanalytical determinants on zymographic analysis of plasma matrix metalloproteinases [Letter]. Clin Chem 2003;49:1956–7. 4. Galewska Z, Romanowicz L, Bankowski E, Jaworski S. Preeclampsia-associated decrease of potential collagenolytic and gelatinolytic activit...

Pyoderma gangrenosum is an inflammatory disease that has been found to be associated with many systemic illnesses. The case presented here is of a man with a 20-year history of hidradenitis suppurativa who developed pyoderma gangrenosum. The pyoderma lesions appeared as a single outbreak which resolved totally after immunosuppressive treatment. This association has been reported only rarely in ...

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BACKGROUND Antibiotics overuse is a global public health issue influenced by several factors, of which some are parent-related psychosocial factors that can only be measured using valid and reliable psychosocial measurement instruments. The PAPA scale was developed to measure these factors and the content validity of this instrument was assessed. AIM This study further validated the recently ...

The conceptual understanding of museums as ‘contact zones’ has been widely appropriated in the museum literature and beyond. But the discussion lacks empirical insights into actual experiences: What does ‘contact’ mean for the person experiencing it? How is it lived, negotiated and contested? Drawing on a long-term narrative study of global visitors to the Museum of New Zealand Te Papa Tongarew...

Tumor suppressors block the development of cancer and are often lost during tumor development. Papa et al. show that partial loss of normal PTEN tumor suppressor function can be compounded by additional disruption caused by the expression of inactive mutant PTEN protein. This has significant implications for patients with PTEN gene mutations.