A number of radioisotopes have recently become commercially available as alternatives to radium-225 in moisture gauging devices using alpha-neutron sources for determining soil moisture, for well logging, and for other industrial applications in which hydrogenous materials are measured. To date, little work has been reported on 21 the comparability of data obtained with different sources when u...

Changes in vegetation structure and composition affect habitat for wildlife. Species such as small mammals that are restricted to small home ranges and are relatively immobile may be most affected since it is more difficult to find and move to new habitat. In the southwestern United States, forest management treatments (thinning and prescribed burning) are being implemented to alter structure a...

We read with interest the encouraging results from POLYP 1 and 2 phase 3 trials omalizumab over 24 weeks in 265 patients allergic chronic rhinosinusits nasal polyposis (CRSwNP), showing significant superiority versus placebo on all primary secondary end points.1Gevaert P. Omachi T.A. Corren J. Mullol Han Lee S.E. et al.Efficacy safety of polyposis: two randomized III trials.J Allergy Clin Immun...

The importance of community engagement in global health research cannot be deemphasized.1Adebisi Y.A. Rabe A. Lucero-Prisno III, D.E. Risk communication and strategies for COVID-19 13 African countries.Health Promot Perspect. 2021; 11: 137-147Google Scholar, 2Adhikari B. Pell C. Cheah P.Y. Community ethical research.Global Bioeth. 2019; 31: 1-12Google 3Tindana P.O. Singh J.A. Tracy C.S. et al.G...

When fitting hierarchical regression models, maximum likelihood estimation has computational (and, for some users, philosophical) advantages compared with full Bayesian inference, but when the number of groups is small, estimates of the covariance matrix (Σ) of group-level varying coefficients are often degenerate. One can do better, even from a purely point-estimation perspective, by using a p...

Anaphylaxis is a serious, systemic, hypersensitivity reaction that can be lifethreatening.1 Understanding the clinical characteristics and triggers associated to it could lead to early recognition and better management. Although the anaphylaxis in western countries is well studied, the clinical features of this condition in Asia started to be investigated just 10 years ago. Recent epidemiologic...

Chronic headache, defined by the presence of headache on at least 15 days per month (1), is a widespread problem affecting approximately 4% of adults (2). Epidemiology studies demonstrate that medication overuse plays a role in a quarter to a third of these cases (3,4), indicating that it is a substantial contributor to the burden of chronic headache. Medication overuse headache (MOH) is identi...

The skin constitutes the first barrier between our organism and the environment. The epidermis consists mainly by keratinocytes that play an essential role in epidermal renewal and skin's defence, actively participating in the cutaneous immune responses through the expression of a variety of cytokines/chemokines. Despite their protective role, keratinocytes are also relevant to the pathogenesis...

TOPIC: Allergy and Airway TYPE: Medical Student/Resident Case Reports INTRODUCTION: In 2018, dupilumab became the first fully human monoclonal antibody targeting both IL-4 IL-13 cytokines which initiate type 2 helper T-cell inflammatory pathways behind eosinophilic allergic diseases. The beneficial effects of for treating atopic dermatitis refractory asthma have been well recognized (1,2), but ...