objective: ionizing radiation produces free radicals which induce dna damage and cell death. origanum vulgare leaf extract (ovle) is a natural compound and its capability of scavenging free radicals and its antioxidant activity have been demonstrated by many researchers. in this study, using micronucleus assay, radioprotective effect of ovle against clastogenic and cytotoxic effect of gamma irr...

Radioprotecting ability of the natural polyphenol, gallic acid (3,4,5-trihydroxybenzoic acid, GA), was investigated in Swiss albino mice. Oral administration of GA (100 mg/kg body weight), one hour prior to whole body gamma radiation exposure (2-8 Gy; 6 animals/group), reduced the radiation-induced cellular DNA damage in mouse peripheral blood leukocytes, bone marrow cells, and spleenocytes as ...

In experiments on mice the study of radioprotective and radiotherapeutic efficacy combined use selenium-containing feed additive DAFS-25k iodine-containing preparation Monclavit-1 was carried out. It has been shown that intragastric administration oil solution 3 hours before total, external, single exposure to γ-radiation, subsequent (in 12 hours) an aqueous Monclavit-1, increases survival rate...

Human beings are at risk of the exposure of radiation or radioactive materials since the World War II. Nuclear proliferation and terrorist activities has further strengthened the threats of the exposure of ionizing radiation (IR) to military, civilian, and emergency responders. IR possesses sufficient energy to strip electrons from atoms or molecules and thereby create highly reactive ions. IR ...