The aminothiol, amifostine (Ethyol; U.S. Bioscience, West with the three-times-a-week dose schedule. Fourteen paConshohocken, PA), is a cytoprotective agent that ameliotients had a 50% or greater increase in absolute neutrophil rates the toxicities of anticancer therapy. In vitro, amifostine count with amifostine treatment (range, 426 to 11,348/mL). promotes the formation and survival of primit...

Material from 63 cases with primary myelodysplastic syndromes (P-MDS) (French-American-British [FAB] types: refractory anemia [RA] = 21; RA with ring sideroblasts [RARS] = 8; RA with excess of blasts (RAEB) = 10; RAEB in transformation (RAEBt) = 6; chronic myelomonocytic leukemia [CMML] = 10 and unclassifiable = 8, ie, bone marrow aspiration was inadequate and stringent FAB criteria were not ap...

NCCN All recommendations are category 2A unless otherwise specified. See believes that the best management for any cancer patient is in a clinical trial. Participation in clinical trials is especially encouraged. NCCN To find clinical trials online at NCCN Member Institutions, click here: nccn.org/clinical_trials/physician.html. The NCCN Guidelines are a statement of evidence and consensus of t...

©Copyright 2017 by Turkish Society of Hematology Turkish Journal of Hematology, Published by Galenos Publishing House Received/Geliş tarihi: May 16, 2015 Accepted/Kabul tarihi: June 15, 2015 Address for Correspondence/Yazışma Adresi: Andaç SALMAN M.D., Marmara University Faculty of Medicine, Department of Dermatology, İstanbul, Turkey Phone : +90 216 657 06 06-3533 E-mail : [email protected]...

We read with great interest the paper by Yoshida et al. entitled " Marked upregulation of survivin and Aurora-B kinase are associated with disease progression in the myelodysplastic syndromes ". 1 Aurora kinases are key players in ensuring accurate chromosome segregation during the cell cycle, maintaining genetic integrity in cell division. 2 Over the last few years, much attention has been foc...

Herpes zoster is a common disease caused due to varicella zoster virus (VZV) infection with increasing incidence by age. If the patient has a severe, extended, or treatment-recalcitrant course of herpes zoster, this must be a red flag to search for underlying pathologies. Here, we report about a 64-year-old male patient with diabetes, who came to our emergency department because of general mala...

Karyotypic evolution is a well-known phenomenon in patients with malignant hematological disorders during disease progression. We describe a 50-year-old male patient who had originally presented with pancytopenia in October 1992. The diagnosis of a myelodysplastic syndrome (MDS) FAB subtype RAEB-t was established in April 1993 by histological bone marrow (BM) examination, and therapy with low-d...