Solid phase high explosive (HE) residues from munitions detonation may be a persistent source of soil and groundwater contamination at military training ranges. Saturated soil column tests were conducted to observe the dissolution behavior of individual components (RDX, HMX, and TNT) from two HE formulations (Comp B and C4). HE particles dissolved readily, with higher velocities yielding higher...

The ezrin-radixin-moesin (ERM) family of proteins crosslink actin filaments and integral membrane proteins. Radixin (encoded by Rdx) is the dominant ERM protein in the liver of wildtype mice and is concentrated at bile canalicular membranes (BCMs). Here we show that Rdx( / ) mice are normal at birth, but their serum concentrations of conjugated bilirubin begin to increase gradually around 4 wee...

Background: The COVID-19 pandemic required hospitals to reduce in-person visits. Although most pediatric foot and ankle conditions do not require urgent consultation, clubfoot (CF) relies on early identification treatment. To avoid unnecessary hospital visits for infants, we developed a triage system using standardized clinical photographs of the child’s feet taken by parents clinician review. ...

Monitoring, assessment and prediction of environmental risks that chemicals pose demand rapid and accurate diagnostic assays. A variety of toxicological effects have been associated with explosive compounds TNT and RDX. One important goal of microarray experiments is to discover novel biomarkers for toxicity evaluation. We have developed an earthworm microarray containing 15,208 unique oligo pr...

Abstract Ultraviolet Raman spectroscopy measurements have been taken at DLR in Lampoldshausen to detect NATO SET-237 standard samples of RDX. The main goal was quantify the minimum requirements for an unambiguous identification remote detection (60 cm distance) with a commercial Czerny–Turner spectrometer coupled CCD camera. Well-defined distribution explosives on surfaces tested as standardize...

The unique capability of secondary electrospray ionization (SESI) as a nonradioactive ionization source to detect analytes in both liquid and gaseous samples was evaluated using aqueous solutions of three common military explosives: cyclo-1,3,5-trimethylene-2,4,6-trinitramine (RDX), nitroglycerin (NG) and pentaerythritol tetranitrate (PETN). The adducts formed between the compounds and their re...

Terahertz range of electromagnetic spectrum (0.1 ÷ 10) THz has focused attention of scientists for years because of many interesting features including existence of spectral fingerprints of many materials (also explosives), through clothing imaging and safety for human being. Such advantages are of great importance for biochemical, defense and security related applications. Scanning of pure exp...

The analysis of explosives with ion mobility spectrometry (IMS) directly from aqueous solutions was shown for the first time using an electrospray ionization technique. The IMS was operated in the negative mode at 250 degrees C and coupled with a quadrupole mass spectrometer to identify the observed IMS peaks. The IMS response characteristics of trinitrotoluene (TNT), 2,4-dinitrotoluene (2,4-DN...

To improve the mechanistic understanding of the possible decomposition in the gas phase of the energetic material HMX (octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine), we used ab initio calculations to determine the various unimolecular decomposition channels. We find three distinct mechanisms: (i) homolytic cleavage of N-N bond to form NO2 (M ) 46) and HMR (M ) 250) which subsequently decomp...