Suppose, as an idealization, that sensory intensity is coded in peripheral channels as identical Poisson pulse trains with intensity parameter a power function of signal intensity. Discrimination models based on either an average count computed over a fixed time or an average time computed for a fixed count per channel have difEculty in fitting the Weber function (AI/I versus I) if the free par...

BACKGROUND Subclinical hypothyroidism is defined as an elevated thyroid-stimulating hormone level with a normal thyroxin level without signs or symptoms of hypothyroidism. Although it is well accepted that overt hypothyroidism has a deleterious impact on pregnancy, recent studies indicate that subclinical hypothyroidism may affect maternal and fetal health. Studies suggest an association betwee...

PURPOSE The aim of the present study was to evaluate the predictive value of volume of the specimen/body mass index (VS/BMI) ratio for recurrence after surgical therapy of pilonidal disease. METHODS Ninety-eight patients with primary pilonidal disease were enrolled in this study. The VS/BMI ratio was calculated for each patient. This ratio was defined as the specimen index (SI). VS, BMI and S...

Influence of Imprecision on ROC Curve Analysis for Cardiac Markers, Peter Kupchak, Alan H.B. Wu, Farooq Ghani, L. Kristen Newby, E. Magnus Ohman, and Robert H. Christenson ( Nanogen, Point of Care Diagnostics Division, Toronto, Ontario, Canada; 2 Department of Laboratory Medicine, San Francisco General Hospital/University of California, San Francisco, CA; 3 Bayer Healthcare Corporation, Tarryto...

Recently, the argument has been made that receiver operating characteristic (ROC) analysis should be used to compare the diagnostic performance of different lineup procedures. However, a drawback to ROC analysis is that is requires multiple correct and false ID rates for each lineup procedure being compared. When only a single pair of correct and false ID rates is measured, what dependent measu...

Recent technological advances continue to provide noninvasive and more accurate biomarkers for evaluating disease status. One standard tool for assessing the accuracy of diagnostic tests is the receiver operating characteristic (ROC) curve. Few statistical methods exist to accommodate multiple continuous-scale biomarkers in the framework of ROC analysis. In this paper, we propose a method to in...

Receiver operating characteristic (ROC) analysis of nerve messages is described. The hypothesis that quantum fluctuations provide the only limit to the ability of frog ganglion cells to signal luminance change information is examined using ROC analysis. In the context of ROC analysis, the quantum fluctuation hypothesis predicts (a) the detectability of a luminance change signal should rise prop...

SUMMARY Comparison of the accuracy of two diagnostic tests using the receiver operating characteristic (ROC) curves from two diagnostic tests has been typically conducted using fixed sample designs. On the other hand, the human experimentation inherent in a comparison of diagnostic modalities argues for periodic monitoring of the accruing data to address many issues related to the ethics and ef...

Responses of brisk-sustained cat retinal ganglion cells were examined using receiver operating characteristic (ROC) analysis. Stimuli were brief luminance changes superimposed upon a weak steady pedestal ranging from 27 to 47,000 quanta (507 nm) per second at the cornea. Overall quantum efficiencies of cells ranged up to approximately 13% and were compatible with previous estimates at absolute ...

This paper presents an approach that enables automatic titling of e-mails relying on the morphosyntactic study of real titles. Automatic titling of e-mails has two interests: Titling mails ’no object’ and managing personal information. The method is developed in three stages: Candidate sentences determination for titling, noun phrases extraction in the candidate sentences, and finally, selectin...