Executive dysfunction (ED) in geriatric depression (GD) is common, predicts poor clinical outcomes and often persists despite remission of symptoms. Here we develop a neuroplasticity-based computerized cognitive remediation-geriatric depression treatment (nCCR-GD) to target ED in GD. Our assumption is that remediation of these deficits may modulate the underlying brain network abnormalities sha...

OBJECTIVE To examine the factors associated with the persistence of childhood gender dysphoria (GD), and to assess the feelings of GD, body image, and sexual orientation in adolescence. METHOD The sample consisted of 127 adolescents (79 boys, 48 girls), who were referred for GD in childhood (<12 years of age) and followed up in adolescence. We examined childhood differences among persisters a...

OBJECTIVE To investigate whether gallstone disease (GD) increases the risk of developing cardiovascular disease (CVD) in a large population-based cohort. METHODS A study population including 6,981 patients with GD was identified from The Taiwan National Health Insurance Research Database between 2004 and 2005. GD patients were defined as patients with principal discharge diagnoses of cholelit...

BACKGROUND Galactose-deficient IgA1 (Gd-IgA1) is a critical effector molecule in the pathogenesis of IgA nephropathy (IgAN). Although many researchers have measured serum levels of Gd-IgA1 using snail helix aspersa agglutinin (HAA) lectin-based assay, the lectin-dependent assay has some serious problems in robustness. In this study, we aimed to establish a more robust and stable enzyme-linked i...

BACKGROUND Gadolinium (Gd), with its 7 unpaired electrons in 4f orbitals that provide a very large magnetic moment, is proven to be among the best agents for contrast enhanced MRI. Unfortunately, the most potent MR contrast agent based on Gd requires relatively high doses of Gd. The Gd-chelated to diethylene-triamine-penta-acetic acid (DTPA), or other derivatives (at 0.1 mmole/kg recommended do...

Introduction: Protein cage nanoparticles (PCNs) have shown promise for molecular/cellular imaging of cardiovascular disease and cancer. PCNs incorporating iron oxide have been used as susceptibility agents for MRI, but T1-shortening agents (e.g., Gd-DTPA) are preferred clinically. The PCN structure can incorporate targeting peptides and can also enhance the T1 effect of Gd by slowing rotational...

The gadolinium(III) chelates Gd(dtpaH2), Gd(hfac)3, Gd(tta)3 and Gd(qu)3 with dtpa1⁄4 1,1,4,7,7-diethylenetriaminepentaacetate, hfac1⁄4 hexafluoroacetylacetonate, tta1⁄4 thenoyltrifluoroacetonate and qu1⁄4 8-quinolinolate (or oxinate) show a phosphorescence under ambient conditions. While the UV emission of Gd(dtpaH2) at kmax 1⁄4 312 nm comes from a metal-centered ff state, the bluish (kmax 1⁄4...

The scintillation decay of cerium-doped gadolinium oxyorthosilicate Gd2(Si04)0.Ce is lengthened by the energy transfer from Gd to Ce. To investigate the role of the Gd in the scintillation processes, the Gd was partially replaced by optically inactive rare earth elements, Y and Lu, and the effective transfer rates from Gd to Ce were measured as a function of Gd and Ce concentrations using Wand ...

Liposomes entrapping gadolinium-DTPA (Gd-DTPA) were synthesized from 60 mole percent egg phosphatidylcholine (EPC) and 40 mole percent cholesterol or EPC alone entrapping Gd-DTPA in diameters of 100 and 200 nm. Rats bearing Morris hepatoma in their flanks were imaged by MR pre- and post-contrast with free Gd-DTPA and liposomal Gd-DTPA for up to four hours after IV contrast. Comparison of images...

adsorption and desorption behavior of gd(iii) ionon macroporous weak acid resin (mwar) had been investigated.the influence of operational conditions such as contact time, initial concentration of gd(iii) ion, initial ph of solution and temperature on the adsorption of gd(iii) ion had been examined. experimental data were exploited for kinetic and thermodynamic evaluations related to the adsorpt...