This is the first study to use a combination of digital imaging techniques and vital video microscopy to study hypoxia-induced changes in blood cell concentration, angiogenesis and blood redistribution in entire animals. Zebrafish Danio rerio, which are known to be independent of convective oxygen transport until about 2 weeks post-fertilization, were raised under chronic hypoxia (P(O(2))=8.7 k...

In the course of clinical work with patients suffering from Bright's disease certain questions constantly present themselves which as constantly are left unanswered except by practical decisions of an almost completely arbitrary nature. For instance, how long should a patient be kept in bed when the initial stage of haemorrhagic Bright's disease has passed, when the edema has gone and the blood...

A new HIGEE device-rotating zigzag bed (RZB) was developed in the context of process intensification. The RZB is structurally featured by a combinatorial rotor of one series of baffles attached to a rotating disk with another series to a stationary disk. The novel structure of the RZB determines its many advantages over the other HIGEE devices. The RZB is free of dynamic seal, capable of interm...

INTRODUCTION This report is one of a series on the Flight Analog Project, which is designed to lay the groundwork for a standard bed rest protocol. The Spaceflight Cognitive Assessment Tool for Windows (WinSCAT) is a self-administered battery of tests used on the International Space Station for evaluating cognitive functioning. Here, WinSCAT was used to assess cognitive functioning during exten...

Aims and method To compare admission rates and bed occupancy before and after the introduction of community treatment orders (CTOs) in 37 assertive outreach service patients. The effect of CTOs on treatment adherence and illicit drug use were also evaluated. The views of patients and care coordinators were obtained through a focus group. Results When CTOs were introduced, admission rates fell f...

A disposable porous bed viscometer (PBV) that has rheologic properties related to that of the microvasculature has recently been developed for the measurement of whole blood viscosity (WBV) under conditions of low shear and low stress. The measured endpoint of apparent viscosity with the PBV is the time for a given volume of whole blood to flow a calibrated distance through the porous bed. The ...